Evidence map›Paper›PMID 42018782›Full record

ArticleBiochemistry2026

Profiling Selectivity for the

Nicholas P McCurtin, Ariana Gazaferi, Noah D Novick, Kyungsub Kim, Cammie F Lesser, Rebecca A Scheck

Abstract read
In one paragraph

Article in Biochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nicholas P McCurtinDepartment of Chemistry, School of Arts and Sciences, Tufts University, 62 Talbot Avenue, Medford, Massachusetts 02155, United States.
Ariana GazaferiDepartment of Chemistry, School of Arts and Sciences, Tufts University, 62 Talbot Avenue, Medford, Massachusetts 02155, United States.ORCID 0009-0002-6903-6688
Noah D NovickDepartment of Chemistry, School of Arts and Sciences, Tufts University, 62 Talbot Avenue, Medford, Massachusetts 02155, United States.
Kyungsub KimDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, 150 Harrison Avenue, Boston, Massachusetts 02111, United States.
Cammie F LesserDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, 150 Harrison Avenue, Boston, Massachusetts 02111, United States.ORCID 0000-0002-1702-6333
Rebecca A ScheckDepartment of Chemistry, School of Arts and Sciences, Tufts University, 62 Talbot Avenue, Medford, Massachusetts 02155, United States.ORCID 0000-0003-0916-0572

Funding

Request for Administrative Supplement for Chemical Strategies to Reveal Cellular Glycation and UbiquitinationR35GM158376 · NIGMS · TUFTS UNIVERSITY MEDFORD · PI Rebecca Scheck · 2025 to 2026
$1.3M
NIGMS NIH HHS R35 GM158376
6 · The paper itself

Abstract

Phosphothreonine lyases are a small family of bacterial virulence factors that are secreted into host cells during infection by some Gram-negative pathogens. Phosphothreonine lyases catalyze an irreversible phosphate β-elimination that converts phosphothreonine (pThr) to dehydrobutyrine (Dhb) on host proteins. Here, we explore the substrate profile for OspF, a phosphothreonine lyase secreted during

Indexed as

Bacterial ProteinsShigella flexneriVirulence FactorsHumansSubstrate SpecificityBacterial ProteinsVirulence Factors

Identifiers

PMID42018782
PMCPMC13151050

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.