SynthesisEndocrinology, diabetes & metabolism2026
Gestational Diabetes and Long-Term Risk of Maternal Kidney Disease: Systematic Review and Meta-Analysis of Population Base Cohort Studies.
Synthesis in Endocrinology, diabetes & metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGestational diabetes mellitus (GDM) may increase the risk of maternal chronic kidney disease (CKD). The association of GDM with maternal CKD has been heterogeneous across studies, and this association remains controversial. The aim of this systematic review was to investigate the association of GDM with the risk of maternal CKD.
methodsMEDLINE/PubMed, EMBASE, Scopus and Web of Science were searched, with no time limit, up to 25 August 2025 by two independent investigators to identify studies that had assessed the association of GDM with maternal risk of CKD. Heterogeneity between studies was assessed using Cochrane's Q and I2 tests. Meta-regression was performed to identify factors associated with heterogeneity.
resultsEleven cohort studies involving 21,313,434 participants (1,530,599 (7.2%) GDM) were included. Pooled estimates from eleven studies showed that GDM was significantly associated with an increased risk of maternal CKD (HR: 2.19; 95% CI: 1.7, 2.68; p: 0.001, I
conclusionGestational diabetes mellitus (GDM) with and without DM was significantly associated with an increased risk of maternal CKD. GDM with DM had a synergistic effect on maternal CKD risk. Although GDM was not significantly associated with increased AKI, only three studies were included in the AKI analysis, which may have affected these results by random error and therefore lack sufficient power and evidence to draw conclusions.
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