Evidence map›Paper›PMID 42018117›Full record

ArticleJapanese journal of ophthalmology2026

Risk factors for tube exposure following Baerveldt glaucoma implantation and overlying tissue thickness assessed by anterior segment optical coherence tomography.

Natsumi Murata, Sachi Kojima, Yuji Takihara, Eri Takahashi, Kei-Ichi Nakashima, Toshihiro Inoue

Abstract read
In one paragraph

Article in Japanese journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Natsumi MurataDepartment of Ophthalmology, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556, Japan.
Sachi KojimaDepartment of Ophthalmology, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556, Japan. sachikojima@kumamoto-u.ac.jp.
Yuji TakiharaDepartment of Ophthalmology, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556, Japan.
Eri TakahashiDepartment of Ophthalmology, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556, Japan.
Kei-Ichi NakashimaDepartment of Ophthalmology, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556, Japan.
Toshihiro InoueDepartment of Ophthalmology, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe identified clinical factors associated with tube exposure following Baerveldt glaucoma implantation (BGI) and used anterior segment optical coherence tomography (AS-OCT) to assess postoperative tissue thickness over the tube. STUDY

designRetrospective, single-center cohort study.

methodsIn this single-center retrospective cohort study, 405 eyes underwent BGI (BG101-350) with preserved scleral patch grafts between October 2014 and December 2022. Tube exposure was documented through clinical records and slit-lamp examination. Risk factors were evaluated using Firth's penalized logistic regression. Overlying tissue thickness at 1 year postoperatively was measured via AS-OCT, and its association with clinical variables was analyzed using linear regression.

resultsThe mean follow-up was 630.7 days, and tube exposure occurred in 12 eyes (2.96%). Neovascular glaucoma (NVG) (odds ratio [OR] 5.03, p = 0.033) and anterior chamber (AC) tube insertion (OR 6.07, p = 0.017) were independently associated with exposure. Overlying tissue was significantly thinner with AC insertion compared with ciliary sulcus or pars plana placement (Kruskal-Wallis with Bonferroni-adjusted Dunn's tests; AC vs sulcus, p = 0.039; AC vs pars plana, p < 0.001). Among eyes with AC insertion, prior micropulse transscleral cyclophotocoagulation (MP-CPC) was associated with greater tissue thickness (estimate 0.173; p = 0.032).

conclusionAC insertion and NVG were associated with an increased risk of tube exposure after BGI. AS-OCT revealed thinner tissue over AC-placed tubes, providing a structural basis for this risk. Avoiding AC insertion may reduce exposure; the observed association between prior MP-CPC and thicker tissue requires prospective validation.

Indexed as

Anterior Eye SegmentGlaucomaGlaucoma Drainage ImplantsIntraocular PressurePostoperative ComplicationsTomography, Optical CoherenceAgedAged, 80 and overFemaleFollow-Up StudiesHumansMaleMiddle AgedRetrospective StudiesRisk FactorsVisual AcuityAnterior chamberAnterior segment optical coherence tomographyBaerveldt glaucoma implantationGlaucoma drainage deviceTube exposure

Identifiers

PMID42018117
PMCPMC13616009

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.