Evidence map›Paper›PMID 42017929›Full record

ArticleCartilage2026

The Effect of Curcumin Treatment on Healing in a Rat Distal Femoral Osteochondral Defect Model.

Emin Can Balcı, Ender Alagöz, Abdurrahman Acar, Muhammed Uslu, Ozancan Biçer, Alperen Öztürk, Enes Başer, Busra Yaprak Bayrak

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cartilage, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Emin Can BalcıDepartment of Orthopaedics and Traumatology, Bağcılar Training and Research Hospital, University of Health Sciences, İstanbul, Türkiye.ORCID 0000-0002-1565-9620
Ender AlagözIstanbul Medipol University, İstanbul, Türkiye.
Abdurrahman AcarDepartment of Orthopaedics and Traumatology, Bağcılar Training and Research Hospital, University of Health Sciences, İstanbul, Türkiye.
Muhammed UsluDepartment of Orthopaedics and Traumatology, Bağcılar Training and Research Hospital, University of Health Sciences, İstanbul, Türkiye.
Ozancan BiçerDepartment of Orthopaedics and Traumatology, Bağcılar Training and Research Hospital, University of Health Sciences, İstanbul, Türkiye.
Alperen ÖztürkAğrı Training and Research Hospital, Ağrı, Türkiye.
Enes BaşerSakarya Sadıka Sabancı State Hospital, Sakarya, Türkiye.
Busra Yaprak BayrakDepartment of Pathology, School of Medicine, Kocaeli University, Kocaeli, Turkey.ORCID 0000-0002-0537-3127

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundArticular cartilage injuries often heal with fibrocartilage rather than native hyaline cartilage, resulting in inferior biomechanical properties and increased osteoarthritis risk. Curcumin has anti-inflammatory and antioxidant properties that may support cartilage repair; however, clinical use is limited by poor bioavailability. Micellar formulations enhance systemic absorption.PurposeTo evaluate the effects of orally administered micellar curcumin on structural and molecular markers of osteochondral repair in a rat distal femoral defect model.MethodsThirty-two female Wistar rats were randomly allocated to 4 groups (

Indexed as

cartilage repaircurcuminhyaline cartilageknee jointmicellar formulationosteochondral defectsrats

Identifiers

PMID42017929
PMCPMC13102747

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.