Evidence map›Paper›PMID 42017790›Full record

ReviewJournal of bacteriology2026

CRISPRi and beyond: studying essential gene function in the obligate intracellular bacterium

Adarsh Gopinath, Li Shen, Scot P Ouellette

Abstract readReview
In one paragraph

Review in Journal of bacteriology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Adarsh GopinathDepartment of Pathology, Microbiology, and Immunology, College of Medicine, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Li ShenDepartment of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA.ORCID 0000-0001-9869-7317
Scot P OuelletteDepartment of Pathology, Microbiology, and Immunology, College of Medicine, University of Nebraska Medical Center, Omaha, Nebraska, USA.ORCID 0000-0002-3721-6839

Funding

Investigating the function of bacterial cytoskeletal elements in the division and growth of the FtsZ-less ChlamydiaR35GM151971 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Scot P Ouellette · 2024 to 2026
$1.2M
CRISPR interference of essential stage-specific gene function in Chlamydia trachomatisR21AI175651 · NIAID · LSU HEALTH SCIENCES CENTER · PI SHEN, LI · 2023 to 2024
$429k
NIGMS NIH HHS R35 GM151971NIH HHS R21AI175651NIH HHS R35GM151971
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Chlamydia trachomatisClustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsGenes, EssentialChlamydia InfectionsGene Knockdown TechniquesGene Knockout TechniquesHumansChlamydiaconditional knockoutCRISPR interference (CRISPRi)DOPEessential geneFRAEMgene knockdownsmall RNA

Identifiers

PMID42017790
PMCPMC13158948

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.