ArticleMicrobiology spectrum2026
Genomic, virologic, and epidemiologic surveillance to track intrafamilial Mpox, Brazil.
Adriana de Souza Andrade, Mariella Sousa Coêlho Maciel, Ana Gabriella Stoffella-Dutra, Silvia Hees de Carvalho, Aline Almeida Bentes, Paulo Emilio Tonaco Costa, Iago José da Silva Domingos, Pedro Henrique Bastos E Silva, Talita Émile Ribeiro Adelino, Felipe Campos de Melo Iani and 5 more
Abstract readCase Reports
In one paragraphArticle in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
15 authors.
Adriana de Souza Andrade *Fundação Oswaldo Cruz, Instituto René Rachou, Belo Horizonte, Minas Gerais, Brazil.
Mariella Sousa Coêlho Maciel *Fundação Oswaldo Cruz, Instituto René Rachou, Belo Horizonte, Minas Gerais, Brazil.ORCID 0000-0003-0509-5339 Ana Gabriella Stoffella-DutraInstituto Nacional de Ciência e Tecnologia em Poxvírus, Belo Horizonte, Brazil.
Silvia Hees de CarvalhoInstituto Nacional de Ciência e Tecnologia em Poxvírus, Belo Horizonte, Brazil.
Aline Almeida BentesInstituto Nacional de Ciência e Tecnologia em Poxvírus, Belo Horizonte, Brazil.
Paulo Emilio Tonaco CostaFundação Hospitalar do Estado de Minas Gerais - Hospital Infantil João Paulo II, Belo Horizonte, Minas Gerais, Brazil.
Iago José da Silva DomingosInstituto Nacional de Ciência e Tecnologia em Poxvírus, Belo Horizonte, Brazil.
Pedro Henrique Bastos E SilvaInstituto Nacional de Ciência e Tecnologia em Poxvírus, Belo Horizonte, Brazil.
Talita Émile Ribeiro AdelinoInstituto Nacional de Ciência e Tecnologia em Poxvírus, Belo Horizonte, Brazil.
Felipe Campos de Melo IaniInstituto Nacional de Ciência e Tecnologia em Poxvírus, Belo Horizonte, Brazil.
Luiz Carlos Júnior AlcantaraFundação Oswaldo Cruz, Instituto René Rachou, Belo Horizonte, Minas Gerais, Brazil.
Giliane de Souza TrindadeInstituto Nacional de Ciência e Tecnologia em Poxvírus, Belo Horizonte, Brazil.
Mauricio Teixeira LimaInstituto Nacional de Ciência e Tecnologia em Poxvírus, Belo Horizonte, Brazil.ORCID 0000-0002-0830-3909 Marco Antônio CamposFundação Oswaldo Cruz, Instituto René Rachou, Belo Horizonte, Minas Gerais, Brazil.ORCID 0000-0003-4683-0176 Funding
Conselho Nacional de Desenvolvimento Científico e Tecnológico 157696/2025-1Conselho Nacional de Desenvolvimento Científico e Tecnológico 310098/2021-4Conselho Nacional de Desenvolvimento Científico e Tecnológico 406441//2022-7Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 88882348380/2010-1Fundação de Amparo à Pesquisa do Estado de Minas Gerais 79170825/2023Ministério de Ciência e Tecnologia, Brazil 405249/2022-5
6 · The paper itselfAbstract
Here, we report a fatal case of IMPORTANCE: Mpox expanded globally in 2022, but pediatric and household transmission remains poorly defined. We report a fatal infection in an immunocompromised patient with advanced HIV/AIDS during the epidemic in Brazil. Integrated clinical and genomic investigations revealed intrafamilial spread within a multigenerational household, including a 3-year-old child who had no direct contact with the index case. Viral genomes clustered in lineage B.1.9, and neutralizing antibodies were detected in an older woman and domestic animals. These findings highlight the potential for household transmission beyond recognized risk groups and underscore the need for strengthened surveillance.
Indexed as
Mpox, MonkeypoxBrazilChild, PreschoolCoinfectionEpidemiological MonitoringFatal OutcomeFemaleGenome, ViralGenomicsHumansImmunocompromised HostPhylogenydisease transmissionhouseholdisolationMpoxOrthopoxviruswhole genome sequencing
Identifiers
PMID42017783
PMCPMC13227957
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390