ArticleMicrobiology spectrum2026
HIV epidemic and needs beyond fast-track cities: a transmission network analysis to study the dynamics of HIV clusters in a French region near Paris.
Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The Centre-Loire Valley region is a low-density demographic and medical region near the fast-track city of Paris, with persistent elevated rates of positive HIV testing. We investigated the role and characteristics of transmission clusters in the HIV dynamics in this region for appropriate local response. HIV pol gene sequences collected in Centre-Loire Valley over a decade (2010-2020) were included in a phylogenetic analysis combined with epidemiological data. Putative transmission clusters were inferred using HIV Transmission Cluster Engine methods. Risk factors of being part of a cluster were studied using multivariate logistic regression models. Of the 1,305 participants, 579 (44%) were born in France, mainly from sub-Saharan Africa; 494 (38%) were women; 433 (33%) were men who have sex with men (MSM); and 694 (53%) were heterosexuals. Migrants had lower CD4 cell count at diagnosis than those born in France (296 vs 443,
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