Evidence map›Paper›PMID 42017243›Full record

ArticleJACC. Case reports2026

TAVR for Elderly Patient With Bicuspid Aortic Stenosis, Severe Horizontal Heart, and Ascending Aorta Dilation.

Xinyi Tang, Qing Lu, Huayiyang Zou, Jing Shi, Yonghong Yong, Wei Sun, Hao Zhang, Xiangqing Kong

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xinyi TangDepartment of Cardiology, Jiangsu Province Hospital, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Qing LuDepartment of Cardiology, Jiangsu Province Hospital, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Huayiyang ZouDepartment of Cardiology, Jiangsu Province Hospital, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Jing ShiDepartment of Cardiology, Jiangsu Province Hospital, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Yonghong YongDepartment of Cardiology, Jiangsu Province Hospital, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Wei SunDepartment of Cardiology, Jiangsu Province Hospital, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Hao ZhangDepartment of Cardiology, Jiangsu Province Hospital, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China. Electronic address: haozhanghh@163.com.
Xiangqing KongDepartment of Cardiology, Jiangsu Province Hospital, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTranscatheter aortic valve replacement (TAVR) has advanced from an emerging technology to a standard therapeutic option for high-risk patients with symptomatic severe aortic stenosis. Procedural risk correlates strongly with aortic root anatomy. In elderly patients with bicuspid aortic valves, concomitant horizontal cardiac orientation and ascending aortic dilation confer markedly higher procedural risk. CASE SUMMARY: We report an elderly patient with a bicuspid aortic valve, severe horizontal aortic root angulation (88°), and ascending aortic dilation (approximately 60 mm). The presence of an ascending aortic aneurysm supported the indication for surgical intervention. Given the substantial technical complexity and perioperative risk of open-heart surgery, TAVR was selected as a safer alternative. DISCUSSION: This case demonstrates that TAVR remains feasible in elderly patients with complex anatomy unsuitable for surgery, despite increased procedural challenges and risk. TAKE-HOME MESSAGE: In elderly patients with severe aortic stenosis and anatomically complex aortic pathology, TAVR should be considered a clinically viable treatment strategy.

Indexed as

bicuspid aortic valvestenosisvalve replacement

Identifiers

PMID42017243
PMCPMC13350391

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.