ArticleClinical kidney journal2026
Poor compliance of recurrent stone formers to increase their fluid intake in spite of repeated recommendation.
Article in Clinical kidney journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The aim of this study was to evaluate 24-h urine volume (UV), estimated osmolarity (eU Methods: Patients of each sex were Results: Mean follow-up was 6.8 years. The 24-h osmolar excretion did not differ between R and NR in either sex, and remained stable between BSL and END. UV was significantly lower in R than NR, both at BSL and END, and eU Conclusion: In conclusion, the patients who showed recurrence of lithiasis not only had lower baseline UV, but were also less able to increase UV than those who did not recur, in spite of recommendations to drink more. Based on preliminary information in the literature, a clinical trial could be designed to evaluate, in these patients, if a low dose of a selective V2 receptor antagonist, increasing their diuresis (and thirst), would prevent new stones.
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