Evidence map›Paper›PMID 42016907›Full record

ArticleAdvanced genetics (Hoboken, N.J.)2026

Antioxidation is a Common Defense Strategy for Different Species Under Mechanical Stress.

Feixiang Zhu, Kai Huang

Abstract read
In one paragraph

Article in Advanced genetics (Hoboken, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Feixiang ZhuInstitute of Mechanobiology & Medical Engineering School of Life Sciences & Biotechnology Shanghai Jiao Tong University Minhang Shanghai China.
Kai HuangInstitute of Mechanobiology & Medical Engineering School of Life Sciences & Biotechnology Shanghai Jiao Tong University Minhang Shanghai China.ORCID https://orcid.org/0009-0001-2257-0843

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mechanical stress, a ubiquitous physical stimulus, triggers oxidative stress through mechanotransduction in diverse organisms, driving the evolution of antioxidant defense systems. This perspective deciphers the molecular evolutionary principles governing these antioxidant strategies, uncovering both conserved and lineage-specific adaptations across biological kingdoms. We demonstrate that redox regulation-an ancient and evolutionarily conserved mechanism-serves as a core defense against mechanical stress-induced oxidative damage, albeit with kingdom-specific variations. Notably, mechanosensors such as Piezo channels are conserved in animals and plants, initiating antioxidant responses via Ca

Indexed as

antioxidant strategymechanical stressmechanotransductionoxidative stress

Identifiers

PMID42016907
PMCPMC13093398

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.