ArticleEFSA journal. European Food Safety Authority2016
Safety and efficacy of manganese compounds (E5) as feed additives for all animal species: manganous carbonate; manganous chloride, tetrahydrate; manganous oxide; manganous sulphate, monohydrate; manganese chelate of amino acids, hydrate; manganese chelate of glycine, hydrate, based on a dossier submitted by FEFANA asbl.
Article in EFSA journal. European Food Safety Authority, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Scientific opinion on the tolerable upper intake level for manganese.EFSA journal. European Food Safety Authority · 2023Article
- Safety and efficacy of a feed additive consisting of manganese(II)-betaine complex for all animal species (Biochem Zusatzstoffe Handels- und Produktionsges. mbH).EFSA journal. European Food Safety Authority · 2023Article
- Sources and trends of trace elements and polycyclic aromatic hydrocarbons in a shallow lake in the Mediterranean area from sediment archives of the Anthropocene.Environmental science and pollution research international · 2022Article
- Safety and efficacy of a feed additive consisting of manganous lysinate sulfate for all animal species (Phytobiotics Futterzusatzstoffe GmbH).EFSA journal. European Food Safety Authority · 2022Article
- Safety and efficacy of a feed additive consisting of manganese chelate of ethylenediamine for all animal species (Zinpro Animal Nutrition (Europe), Inc.).EFSA journal. European Food Safety Authority · 2021Article
- Manganese requirements of broiler breeder hens.Poultry science · 2020Article
- Safety and efficacy of Manganese chelates of lysine and glutamic acid as feed additive for all animal species.EFSA journal. European Food Safety Authority · 2020Article
- Marble industry effluents cause an increased bioaccumulation of heavy metals in Mahaseer (Tor putitora) in Barandu River, district Buner, Pakistan.Environmental science and pollution research international · 2017Article
- Safety and efficacy of manganese hydroxychloride as feed additive for all animal species.EFSA journal. European Food Safety Authority · 2016Article
- Safety and efficacy of manganese compounds (E5) as feed additives for all animal species: manganous carbonate; manganous chloride, tetrahydrate; manganous oxide; manganous sulphate, monohydrate; manganese chelate of amino acids, hydrate; manganese chelate of glycine, hydrate, based on a dossier submitted by FEFANA asbl.EFSA journal. European Food Safety Authority · 2016Article
Corrections and comments
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Authors and funding
1 author.
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Abstract
The Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) has assessed five manganese compounds: manganous chloride, tetrahydrate; manganous sulphate, monohydrate; manganous oxide; manganese chelate of amino acids, hydrate; manganese chelate of glycine, hydrate. The safety assessment is based on the assumption that the current maximum total contents of manganese authorised in feed are respected. All manganese compounds under application are considered safe for all animal species/categories. The mean manganese intake of the European population includes already the manganese from animal products and does not pose a toxicological concern. The effect of dietary manganese fed to animals on tissue concentrations is limited. Supplementation of feed with the manganese compounds under assessment would consequently not affect consumer exposure and is of no concern for consumer safety. All manganese compounds are considered as eye irritants, the manganese chelate of glycine and the manganese chelate of amino acids as irritants to skin and the latter one as dermal sensitiser. However, the presence of nickel in all additives may induce contact dermatitis. Exposure to manganese in dust of all additives and to nickel (except manganous chloride and manganous oxide) poses a risk to users by inhalation. The use of the manganese compounds under assessment in animal nutrition for all animal species is not expected to pose a risk to the environment. The manganese compounds under assessment are recognised as efficacious sources of manganese in meeting animals' requirements.
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