ReviewBioengineering & translational medicine2026
Overcoming challenges in cartilage regeneration: The role of chondrogenic inducers.
Review in Bioengineering & translational medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Functional Biomaterials and 3D Bioprinting Approaches for Temporomandibular Joint Reconstruction: A Narrative Review.Journal of functional biomaterials · 2026Review
- Exploring cartilage development and disease models: applications of cartilage organoids.Inflammation and regeneration · 2026Review
- Mechanotransduction and its impact on regenerative medicine in orthopedic rehabilitation (Review).International journal of molecular medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cartilage regeneration presents unique challenges due to its avascular structure, sparse cell population, and limited regenerative capacity. Recent years have seen significant advancements in the field, which warrant an integrated review that connects chondrogenesis and its practical application. This review aims to deliver comprehensive and analytical guidelines for understanding the complex process of chondrogenesis, emphasizing its critical role in cartilage regeneration. It reviews key inducers such as growth factors, mechanical stimuli, hypoxia, and electric fields, as well as their synergistic integration with biomaterials to facilitate effective strategies for repairing and regenerating damaged cartilage tissue. In addition to exploring these advancements, the paper also provides a critical evaluation of current methods used to assess chondrogenesis in in vitro and in vivo models, identifying gaps and possibilities for improvement. A particular focus is placed on addressing the translational challenges that hinder the clinical implementation of cutting-edge research findings, offering actionable strategies to bridge the gap between laboratory discoveries and patient outcomes. By examining emerging trends and consolidating recent innovations, this review aims to offer a holistic perspective on cartilage repair. It serves as a guide for researchers and clinicians, advocating for collaborative, interdisciplinary approaches to advance the field and deliver improved therapeutic solutions for cartilage-related conditions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.