Evidence map›Paper›PMID 42016854›Full record

ArticleBioengineering & translational medicine2026

Olfactory ensheathing cells exosomes enhance neurological recovery in brain-injured rats by modulating Nrf2-ferroptosis pathway.

Xin-Li Chen, Yi-Bin Liu, Cheng-Ye Lin, Shu Lin, He-Fan He, Wei-Feng Liu

Abstract read
In one paragraph

Article in Bioengineering & translational medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xin-Li ChenDepartment of Anesthesiology The Second Affiliated Hospital of Fujian Medical University Quanzhou Fujian China.ORCID https://orcid.org/0009-0005-8962-6740
Yi-Bin LiuDepartment of Anesthesiology The Second Affiliated Hospital of Fujian Medical University Quanzhou Fujian China.ORCID https://orcid.org/0009-0001-3262-0947
Cheng-Ye LinDepartment of Orthopedics The Second Affiliated Hospital of Fujian Medical University Quanzhou Fujian China.ORCID https://orcid.org/0009-0005-0886-5951
Shu LinGroup of Neuroendocrinology Garvan Institute of Medical Research Sydney New South Wales Australia.ORCID https://orcid.org/0000-0002-4239-2028
He-Fan HeDepartment of Anesthesiology The Second Affiliated Hospital of Fujian Medical University Quanzhou Fujian China.ORCID https://orcid.org/0000-0003-0787-3173
Wei-Feng LiuDepartment of Anesthesiology The Second Affiliated Hospital of Fujian Medical University Quanzhou Fujian China.ORCID https://orcid.org/0000-0001-5676-6978

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate the therapeutic potential of the olfactory ensheathing cells (OECs) exosomes (EXOs) in traumatic brain injury (TBI) and the regulatory role of nuclear factor E2-related factor (Nrf2). Rats were divided into Sham, TBI, OECs-EXOs (EXO), and OECs-EXOs plus Nrf2 inhibitor (ML385) groups. Neurological function was assessed using the modified neurological severity score, the Morris water maze (MWM), and the Barnes maze tests. Brain injury, Fe

Indexed as

exosomesferroptosisNrf2 pathwayolfactory ensheathing cellstraumatic brain injury

Identifiers

PMID42016854
PMCPMC13093426

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.