Evidence map›Paper›PMID 42016793›Full record

ReviewEngineering in life sciences2026

Molecular Pharming: Advances, Applications, and Future Prospects in Biotechnology and Medicine.

Md Hridoy Ahmed, Md Mustak Khan, Shishir Dutta, Md Foyzur Rahman, Mohammad Shariful Islam, Md Najmul Hosen, Md Saad Hossain, Md Aftabur Rahman, Md Sadman Hasan Sahil, Tanjuma Tasnim Hira and 4 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Engineering in life sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Md Hridoy AhmedDepartment of Genetic Engineering and Biotechnology University of Chittagong Chittagong Bangladesh.ORCID https://orcid.org/0000-0003-2077-4401
Md Mustak KhanDepartment of Biochemistry and Molecular Biology University of Chittagong Chittagong Bangladesh.
Shishir DuttaDepartment of Soil Science University of Chittagong Chittagong Bangladesh.
Md Foyzur RahmanDepartment of Pharmacy Dhaka International University Dhaka Bangladesh.ORCID https://orcid.org/0009-0006-5381-0260
Mohammad Shariful IslamDepartment of Zoology University of Chittagong Chittagong Bangladesh.
Md Najmul HosenDepartment of Biochemistry and Biotechnology University of Science and Technology Chittagong Bangladesh.
Md Saad HossainDepartment of Genetic Engineering and Biotechnology East West University Dhaka Bangladesh.
Md Aftabur RahmanDepartment of Biotechnology and Genetic Engineering Jahangirnagar University, Savar Dhaka Bangladesh.
Md Sadman Hasan SahilFaculty of Pharmacy Jashore University of Science and Technology Jashore Bangladesh.
Tanjuma Tasnim HiraFaculty of Fisheries Bangladesh Agricultural University Mymensingh Bangladesh.
IfthesumDepartment of Botany University of Chittagong Chittagong Bangladesh.
Ashikur RahamanDepartment of Genetic Engineering and Biotechnology University of Chittagong Chittagong Bangladesh.
Md Afser RabbiDepartment of Biochemistry and Molecular Biology Shahjalal University of Science and Technology Sylhet Bangladesh.
Laila KhaledaDepartment of Genetic Engineering and Biotechnology University of Chittagong Chittagong Bangladesh.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetically engineered plants incorporate the use of a novel bioreactor known as molecular pharming, which has a transformative view on the pharmaceutical industry. The technique enables mass production, at a low cost, and reproducibly of a large number of different protein-based drugs, vaccines, and industrial enzymes. This review-based study outlines the chronological evolution of molecular pharming, investigates its essential principles and elective applications, and meticulously compares it with other methods, namely conventional biomanufacturing. We present the numerous host organisms employed, the leading-edge genetic engineering procedure, and the sophisticated approaches for protein purification and extraction. Additionally, we deliver in-depth analysis of the noteworthy advantages that take place in molecular pharming as a captivating substitute, in conjunction with obstinate challenges, including concerns of public insights, intricate regulatory frameworks, and consideration for economic sustainability. Finally, this comprehensive study explores the promising direction, evolving innovations, and essential areas that influence future research to fully reveal the extensive potential of plant-based biopharmaceutical production for industrial strains and global health.

Indexed as

biopharmingCRISPR/Cas9genetic engineeringmolecular pharmingplant‐based biopharmaceuticalsplant expression systemsrecombinant protein productiontransgenic plantsvaccine development

Identifiers

PMID42016793
PMCPMC13093607

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.