Evidence map›Paper›PMID 42016765›Full record

ArticleExploration (Beijing, China)2026

PSMA-Targeting Macrophage Membrane-Coated Nanoparticles for Precision Diagnosis and Combination Therapy of Prostate Cancer.

Keying Zhang, Bo Gao, Jingwei Wang, Yu Li, Chao Xu, Fa Yang, Shaojie Liu, Hongji Li, Chao Zhang, Xiangliang Meng and 10 more

Abstract read
In one paragraph

Article in Exploration (Beijing, China), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Keying ZhangDepartment of Urology Xijing Hospital Fourth Military Medical University Xi'an China.
Bo GaoInstitute of Orthopaedic Surgery Xijing Hospital Fourth Military Medical University Xi'an China.
Jingwei WangThe First Affiliated Hospital Southern University of Science and Technology Shenzhen China.
Yu LiDepartment of Urology Xijing Hospital Fourth Military Medical University Xi'an China.
Chao XuDepartment of Urology Xijing Hospital Fourth Military Medical University Xi'an China.
Fa YangDepartment of Urology Xijing Hospital Fourth Military Medical University Xi'an China.
Shaojie LiuDepartment of Urology Xijing Hospital Fourth Military Medical University Xi'an China.
Hongji LiDepartment of Urology Xijing Hospital Fourth Military Medical University Xi'an China.
Chao ZhangDepartment of Urology Xijing Hospital Fourth Military Medical University Xi'an China.
Xiangliang MengDepartment of Urology Xijing Hospital Fourth Military Medical University Xi'an China.
Zhaokun ShiDepartment of Urology Xijing Hospital Fourth Military Medical University Xi'an China.
Rui ZhangState Key Laboratory of Cancer Biology Department of Immunology Fourth Military Medical University Xi'an China.ORCID https://orcid.org/0000-0002-6147-1573
Ruili ZhangEngineering Research Center of Molecular & Neuroimaging Ministry of Education School of Life Science and Technology Xidian University Xi'an China.
Zhongliang WangEngineering Research Center of Molecular & Neuroimaging Ministry of Education School of Life Science and Technology Xidian University Xi'an China.
Weihong WenInstitute of Medical Research Northwestern Polytechnical University Xi'an China.
Qiang ZhangDepartment of Medicine Division of Hematology/Oncology Northwestern University Feinberg School of Medicine Chicago, IL USA.
Yuankang ZouDepartment of Occupational and Environmental Health and the Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment School of Public Health Fourth Military Medical University Xi'an China.
Donghui HanDepartment of Urology Xijing Hospital Fourth Military Medical University Xi'an China.
Huijie BianNational Translational Science Center for Molecular Medicine & Department of Cell Biology Fourth Military Medical University Xi'an China.
Weijun QinDepartment of Urology Xijing Hospital Fourth Military Medical University Xi'an China.ORCID https://orcid.org/0000-0002-7509-7164

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer (PCa) is the most frequently diagnosed cancer in males. Advanced PCa is invasive and may spread rapidly. Current strategies could not fulfill the requirement for clinical application; thus, novel therapeutic strategies are still urgently needed. Nanoparticles are a promising strategy for targeted drug delivery and cancer treatment; however, the strong exogeneity and weak targeting limit their further application. Here, we developed a novel macrophage membrane-coated nanoparticle that has transmembrane-expressed gy-1, a single-chain antibody fragment (scFv) against prostate-specific membrane antigen (PSMA), to endow the immune evasion and targeting property, which we named P-MMCNPs. The Fe

Indexed as

combined treatmentimmunomodulationmacrophage membrane‐coated nanoparticleprostate cancerprostate‐specific membrane antigentargeted multimodal imaging

Identifiers

PMID42016765
PMCPMC13094533

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.