Evidence map›Paper›PMID 42016759›Full record

ArticleExploration (Beijing, China)2026

Bacterial Biohybrids With Dual Magnet and Hypoxia Tropism for Ferroptosis Activation in Deep Tumor Regions.

Sijie Shao, Huilan Zhuang, Tingjie Bai, Xuemei Zeng, Angelo Homayoun All, Shuangqian Yan

Abstract read
In one paragraph

Article in Exploration (Beijing, China), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sijie ShaoStrait Institute of Flexible Electronics (SIFE Future Technologies) Fujian Key Laboratory of Flexible Electronics Fujian Normal University and Strait Laboratory of Flexible Electronics (SLoFE) Fuzhou China.
Huilan ZhuangStrait Institute of Flexible Electronics (SIFE Future Technologies) Fujian Key Laboratory of Flexible Electronics Fujian Normal University and Strait Laboratory of Flexible Electronics (SLoFE) Fuzhou China.
Tingjie BaiStrait Institute of Flexible Electronics (SIFE Future Technologies) Fujian Key Laboratory of Flexible Electronics Fujian Normal University and Strait Laboratory of Flexible Electronics (SLoFE) Fuzhou China.
Xuemei ZengKey Laboratory of Microbial Pathogenesis and Interventions of Fujian Province University, Biomedical Research Center of South China College of Life Sciences Fujian Normal University Fuzhou P. R. China.
Angelo Homayoun AllDepartment of Chemistry Hong Kong Baptist University Hong Kong SAR China.
Shuangqian YanStrait Institute of Flexible Electronics (SIFE Future Technologies) Fujian Key Laboratory of Flexible Electronics Fujian Normal University and Strait Laboratory of Flexible Electronics (SLoFE) Fuzhou China.ORCID https://orcid.org/0009-0003-7306-7265

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Effectively delivering therapeutics to deep tumor regions is crucial for successful treatment but remains a formidable challenge. The severe hypoxia common in these areas can inhibit various therapeutic-induced cell death pathways, including ferroptosis. Herein, we present the design of a bacterial biohybrid (Ec@ZFOY) with dual magnetic and hypoxic tropism for targeted therapeutic delivery and ferroptosis activation in the deep tumor region. This biohybrid is constructed using hypoxia-targeted

Indexed as

bacterial biohybridsferroptosishypoxiatumor penetration

Identifiers

PMID42016759
PMCPMC13094518

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.