Evidence map›Paper›PMID 42016678›Full record

ArticleClinical case reports2026

Lymphangioma-Induced Macroglossia in an Adolescent: A Case Report.

Arezoo Heidary, Mojtaba Mehrabanian

Abstract read
In one paragraph

Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Arezoo HeidaryDepartment of Oral and Maxillofacial Diseases, Faculty of Dentistry Yazd Shahid Sadoughi University of Medical Sciences Yazd Iran.ORCID https://orcid.org/0000-0002-7762-372X
Mojtaba MehrabanianDental Research Center, Dental Research Institute, School of Dentistry Isfahan University of Medical Sciences Isfahan Iran.ORCID https://orcid.org/0000-0002-3095-9111

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lymphangioma is a congenital malformation of the lymphatic system, commonly affecting the head and neck region. Macroglossia due to lymphangioma in adolescence is uncommon, making this case noteworthy. This condition can affect oral function, speech, and quality of life, making early diagnosis and intervention essential. This report highlights a 14-year-old Balouch female presenting with progressive tongue enlargement beginning at age five. Intraoral examination revealed an enlarged tongue with a pebbly surface, particularly involving the ventral side of the tongue, without osseous involvement on radiographs. Differential diagnoses included hemangioma and lymphangiomegaly; however, histopathological analysis confirmed lymphangioma. The patient underwent sclerotherapy, resulting in a significant reduction in tongue size, improved oral function, and resolution of related symptoms. Follow-up revealed no recurrence or major complications. Early recognition and appropriate management of lymphangioma-induced macroglossia are essential to prevent functional limitations and improve quality of life. While surgical excision remains the conventional treatment, sclerotherapy offers a less invasive, effective alternative with lower morbidity. This case contributes to the limited literature on adolescent-onset oral lymphangioma and underscores the value of a multidisciplinary approach in ensuring optimal outcomes.

Indexed as

hamartomalymphangiomalymphatic malformationmacroglossiasclerotherapy

Identifiers

PMID42016678
PMCPMC13093627

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.