Evidence map›Paper›PMID 42016653›Full record

ArticleClinical case reports2026

From Diagnostic Challenge to Clinical Success: Rapid Multiplex PCR Identification of Cryptosporidium in HIV-Associated Refractory Diarrhea: A Case Report.

Yudai Kono, Mayu Arase, Kohei Ukai, Keiko Soneda, Shinya Yamamoto, Kazuhiko Ikeuchi, Eisuke Adachi, Yusuke Nomura, Yoshimi Higurashi, Shinji Izumiyama and 7 more

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Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Yudai KonoDepartment of Infectious Diseases The University of Tokyo Hospital Tokyo Japan.
Mayu AraseDepartment of Infectious Diseases The University of Tokyo Hospital Tokyo Japan.
Kohei UkaiDepartment of Infectious Diseases The University of Tokyo Hospital Tokyo Japan.
Keiko SonedaDepartment of Infectious Diseases The University of Tokyo Hospital Tokyo Japan.
Shinya YamamotoDepartment of Infectious Diseases The University of Tokyo Hospital Tokyo Japan.ORCID https://orcid.org/0000-0003-2890-7256
Kazuhiko IkeuchiDepartment of Infectious Diseases The University of Tokyo Hospital Tokyo Japan.
Eisuke AdachiDepartment of Infectious Diseases and Applied Immunology, IMSUT Hospital The Institute of Medical Science, the University of Tokyo Tokyo Japan.
Yusuke NomuraDepartment of Infection Control and Prevention The University of Tokyo Hospital Tokyo Japan.
Yoshimi HigurashiDepartment of Infection Control and Prevention The University of Tokyo Hospital Tokyo Japan.
Shinji IzumiyamaDepartment of Parasitology National Institute of Infectious Diseases Tokyo Japan.
Kazuki HonjoDepartment of Gastroenterology The University of Tokyo Hospital Tokyo Japan.
Yu MiyakawaDepartment of Gastroenterology The University of Tokyo Hospital Tokyo Japan.
Sozaburo IharaDepartment of Gastroenterology The University of Tokyo Hospital Tokyo Japan.
Hiroyuki AbeDepartment of Pathology The University of Tokyo Hospital Tokyo Japan.
Mitsuhiro FujishiroDepartment of Gastroenterology The University of Tokyo Hospital Tokyo Japan.
Shu OkugawaDepartment of Infectious Diseases The University of Tokyo Hospital Tokyo Japan.
Takeya TsutsumiDepartment of Infectious Diseases The University of Tokyo Hospital Tokyo Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cryptosporidiosis remains a challenge in people with HIV despite its decreased incidence in developed countries. We report a case of severe diarrhea in a person with HIV where Gram stain findings prioritized cryptosporidium in the differential diagnosis. Multiplex PCR enabled early diagnosis and treatment, highlighting its value in clinical management.

Indexed as

cryptosporidiumgram stainHIVmultiplex PCR

Identifiers

PMID42016653
PMCPMC13093272

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.