ArticleImaging neuroscience (Cambridge, Mass.)
Sex-specific associations of gestational age at birth and birth size with early life within-network brain connectivity: An exploratory study.
Article in Imaging neuroscience (Cambridge, Mass.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Gestational age at birth and birth size are major risk factors for early life behavioral/cognitive problems, but their impact on functional brain network dynamics during this period is not understood. Our objective was to conduct an exploratory study to evaluate associations of birth measures with longitudinal early life functional connectivity. The Baby Connectome Project used resting-state functional magnetic resonance imaging to assess connectivity within seven canonical brain networks (Yeo atlas): dorsal attention, salience, limbic, frontoparietal, default mode, visual, and sensorimotor. For 254 children <3 years old (contributing 583 observations), birth weight, birth length, and gestational age at birth were self-reported or abstracted from medical records, and we calculated weight-to-length ratio. Using covariate-adjusted multiple linear mixed models, we evaluated overall and sex-specific associations of birth measures as continuous variables and in tertiles with each network, which were Fisher
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