Evidence map›Paper›PMID 42016281›Full record

ArticleCritical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine2026

Sustainable continuous renal replacement therapy: The influence of blood flow rates, effluent dose, autoeffluent, and citrate anticoagulation on carbon dioxide emissions.

Cyveen Weeraratna, Forbes McGain, Andrew A Udy, Emily J See, Christian Karcher, Patrick R Joyce, Scott McAlister, Catherine J O'Shea, Mayuri G W Wijayasundara, Natalie Adams and 2 more

Abstract read
In one paragraph

Article in Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Balancing carbon reduction and treatment adequacy in sustainable CRRT.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2026
    Article
  2. Balancing carbon reduction and treatment adequacy in sustainable continuous renal replacement therapy.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Cyveen WeeraratnaIntensive Care Unit, Royal Melbourne Hospital, Victoria, Australia.
Forbes McGainDepartment of Critical Care, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Australia.
Andrew A UdyIntensive Care Medicine, Alfred Hospital, Melbourne, Victoria, Australia.
Emily J SeeIntensive Care Medicine - Royal Melbourne Hospital, Victoria, Australia.
Christian KarcherIntensive Care Medicine - Royal Melbourne Hospital, Victoria, Australia.
Patrick R JoyceIntensive Medicine, Alfred Hospital, Melbourne, Victoria, Australia.
Scott McAlisterHealthcare Sustainability, University of Melbourne, Victoria, Australia.
Catherine J O'SheaUniversity of Melbourne, Victoria, Australia.
Mayuri G W WijayasundaraDeakin University, Sustainability and Circular Economy, Australia.
Natalie AdamsIntensive Care Unit, Alfred Hospital, Melbourne, Victoria, Australia.
Susan R JamesIntensive Care Unit, Alfred Hospital, Melbourne, Victoria, Australia.
Benjamin W SansomRoyal Melbourne Hospital, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The aim of this study was to quantify the consumables waste for continuous renal replacement therapy (CRRT) in intensive care, determine the carbon dioxide equivalent (CO Design: A retrospective observational study was conducted. Setting: The study included two major tertiary intensive care units in Melbourne from January 2017 to December 2024. Participants: We analysed 70,000 h of treatment data stored on CRRT machines, captured from 2464 patients. Interventions: Quantities of all major consumables were obtained. A chemical composition analysis was performed, and life cycle analysis was done for each component. Main outcome measures: Carbon dioxide-equivalent values and financial cost estimates were calculated using local, commercial pricing. Results: Combined impact of autoeffluent, lowest effluent rate (<30 mL/kg/hr), and doubling of filter life linked to Q Conclusion: Extended circuit lifespan, autoeffluent, and moderated effluent doses translate to the most sustainable delivery of CRRT with associated cost savings.

Indexed as

Carbon dioxide equivalent (CO2-e)ConsumablesContinuous renal replacement therapy (CRRT)Life cycle analysis (LCA)Sustainability in intensive care

Identifiers

PMID42016281
PMCPMC13094636

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.