ArticleCritical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine2026
Association between frailty and long-term outcomes in patients undergoing TAVI admitted to private intensive care units in Australia.
Article in Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Frailty is common in patients undergoing transcatheter aortic valve implantation (TAVI) and may influence post-procedural outcomes. We examined the association between frailty and long-term outcomes among patients admitted to intensive care units (ICUs) following TAVI. Design setting and participants: Retrospective multicentre registry-based cohort study using the Australian and New Zealand Intensive Care Society Adult Patient Database. Adult patients (≥16 years) admitted to private ICUs in Australia following TAVI between 1 January 2018 and 30 June 2024 were included. Main outcome measures: Frailty was assessed using the clinical frailty scale (CFS) and categorised as nonfrail (CFS 1-3), mildly frail (CFS 4-5), or moderately-to-severely frail (CFS 6-8). The primary outcome was survival up to 4 years. Secondary outcomes included in-hospital mortality, hospital length of stay, and discharge destination. Associations between frailty and survival were evaluated using Cox proportional hazards models with robust sandwich estimators. Results: Among 3917 patients, 1598 (40.8%) were nonfrail, 1920 (49.0%) were mildly frail, and 399 (10.3%) were moderately-to-severely frail. Four-year survival was highest among nonfrail patients (73.4%; 95% confidence interval [CI], 70.1-76.8), followed by mildly frail (62.7%; 95% CI, 59.3-66.4; adjusted hazard ratio [aHR], 1.52; 95% CI, 1.33-1.73) and moderately-to-severely frail patients (44.2%; 95% CI, 37.9-51.6; aHR, 2.23; 95% CI, 1.99-2.49). Patients with moderate-to-severe frailty had higher in-hospital mortality, longer hospital stays, and less frequently discharged home. Conclusions: Frailty was common among patients admitted to ICU following TAVI and was independently associated with reduced long-term survival and adverse hospital outcomes. Routine frailty assessment may help inform peri-procedural risk stratification and clinical decision-making in patients undergoing TAVI.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.