Evidence map›Paper›PMID 42016217›Full record

ArticleCase reports in otolaryngology2026

Salvage Frenuloplasty With Porcine Small Intestinal Submucosa Graft in a Newborn Following Unsuccessful Laser Release: A Case Report.

Carlos O'Connor-Reina, Maria Teresa Garcia Iriarte, Laura Rodriguez Alcala, Eduardo Correa, Peter Baptista, Guillermo Plaza

Abstract read
In one paragraph

Article in Case reports in otolaryngology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carlos O'Connor-ReinaOtorhinolaryngology Department, Hospital Quironsalud Marbella, Marbella, 29680, Spain.ORCID https://orcid.org/0000-0002-1670-4235
Maria Teresa Garcia IriarteOtorhinolaryngology Department, Hospital Universitario Virgen de Valme, Sevilla, Spain.ORCID https://orcid.org/0000-0003-4066-0137
Laura Rodriguez AlcalaOtorhinolaryngology Department, Hospital Quironsalud Marbella, Marbella, 29680, Spain.ORCID https://orcid.org/0000-0002-5148-5111
Eduardo CorreaOtorhinolaryngology Department, Hospital Quironsalud Marbella, Marbella, 29680, Spain.ORCID https://orcid.org/0000-0002-6141-5360
Peter BaptistaOtorhinolaryngology Department, Clinica Universitaria de Navarra, Pamplona, Spain, cun.es.ORCID https://orcid.org/0000-0002-6601-5331
Guillermo PlazaOtorhinolaryngology Department, Hospital Universitario de Fuenlabrada, Universidad Rey Juan Carlos Madrid, Madrid, Spain.ORCID https://orcid.org/0000-0001-6409-4921

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: As the number of frenotomy procedures increases worldwide, the recognition and management of potential complications has become increasingly relevant. Postprocedural scarring following laser release may severely restrict tongue mobility in infants and occasionally requires surgical revision. Case Presentation: We report the case of a 3-month-old infant referred for persistent feeding difficulties and poor weight gain (5th percentile) after an unsuccessful laser frenotomy performed elsewhere. Clinical examination revealed severe ankyloglossia secondary to a dense restrictive scar, with a Bristol Tongue Assessment Tool (BTAT) score of 0. Revision surgery was performed under general anesthesia, consisting of complete excision of fibrotic tissue and reconstruction of the ventral tongue using a porcine small intestinal submucosa (SIS) graft to cover the mucosal defect. Intralesional corticosteroid therapy was not considered due to the absence of regulatory approval and limited safety data for intralesional use in infants with oral mucosal fibrosis. At 6-week follow-up, the infant demonstrated restored tongue mobility, normal breastfeeding, improvement of BTAT score to 6, and weight gain to the 50th percentile. At 12-month follow-up, the patient demonstrated sustained functional improvement, normal oral feeding without restriction, appropriate weight gain for age, and no recurrence of fibrotic scarring or tongue mobility limitation. Discussion: In this case, the extent of fibrosis precluded tension-free primary closure. The use of a porcine SIS graft facilitated mucosal coverage and aimed to reduce the risk of recurrent scarring. Given the limited pharmacological options available for neonatal fibrosis management, selected surgical reconstruction strategies may represent a reasonable alternative in severe cases. Conclusion: Porcine SIS grafting may be considered in selected infants presenting with severe postfrenotomy scarring when conventional closure is not feasible. Longer follow-up and additional cases are needed to establish safety and reproducibility.

Indexed as

ankyloglossiabreastfeedingfrenotomyfrenuloplastyporcine small intestinal submucosapostoperative scarringscarringtongue-tie

Identifiers

PMID42016217
PMCPMC13092796

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.