ArticleMethodsX2026
Modification of fish oil triglycerides into 1,2,3-triazole-fatty acid esters as potent antitubercular agents.
Article in MethodsX, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
This study aimed to develop 1,2,3-triazole derivatives from fish oil triglycerides as potential antitubercular agents. The synthetic route consisted of three main steps: hydrolysis of fish oil to obtain free fatty acids (2, yield 86%), propargylation of the free fatty acids to produce propargyl esters (3, yield 59%), and azide-alkyne [3 + 2] cycloaddition of the propargyl esters to afford 1,2,3-triazole esters (5, yield 85%). Linoleic acid was identified as the predominant fatty acid. All compounds were characterized using FTIR, NMR, and HRMS analyses. The final compound (5) demonstrated moderate inhibitory activity against
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