Evidence map›Paper›PMID 42015857›Full record

ReviewDeutsches Arzteblatt international2026

Thyroid Cancer: Epidemiology, Diagnosis, and Treatment.

Katharina Holzer, Viktoria Florentine Koehler, Jörg Bojunga, Markus Luster, Detlef K Bartsch, Friederike Eilsberger

Abstract readReview
In one paragraph

Review in Deutsches Arzteblatt international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Katharina HolzerDepartment of Visceral, Thoracic and Vascular Surgery, Philipps University Marburg, Marburg, Germany
Viktoria Florentine KoehlerMedical Clinic 1— Gastroenterology and Hepatology, Pulmonology and Allergology, Endocrinology and Diabetology, and Nutritional Medicine, University Medical Center Frankfurt
Jörg BojungaMedical Clinic 1— Gastroenterology and Hepatology, Pulmonology and Allergology, Endocrinology and Diabetology, and Nutritional Medicine, University Medical Center Frankfurt
Markus LusterDepartment of Nuclear Medicine, Marburg University Hospital
Detlef K BartschDepartment of Visceral, Thoracic and Vascular Surgery, Philipps University Marburg, Marburg, Germany
Friederike EilsbergerDepartment of Nuclear Medicine, Marburg University Hospital

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThyroid cancer, including carcinoma, metastases, sarcoma, and lymphoma of the thyroid gland, is much rarer (incidence of thyroid carcinoma, ca. 7 per 100 000 people per year in Germany) than benign nodular thyroid disease (prevalence: ca. 10% in young men to 80% in older women). The incidence of differentiated thyroid carcinoma has risen around the world in recent years.

methodsThis narrative review is based on publications retrieved by a search of PubMed.

resultsIn Germany in 2022, approximately 4200 women and 1800 men received a diagnosis of thyroid carcinoma. The relative 10-year survival rate for this disease was 94% in women and 86% in men. Differentiated thyroid carcinoma (DTC), mainly of the papillary subtype (PTC), was the most common type of thyroid carcinoma in Germany (76% in women, 66% in men). Combined surgery and radio-iodine therapy are still the most common treatment for DTC, although initially available prospective studies currently cast doubt on the benefit of radio-iodine therapy in certain risk groups. The option of active surveillance has been introduced for selected patients with a small PTC. The treatment of radio-iodine-refractory, poorly differentiated, and anaplastic thyroid carcinoma has improved with the introduction of targeted molecular therapies and immunotherapeutic drugs.

conclusionThe treatment of thyroid carcinoma has become more individualized, with less aggressive approaches for small tumors and an expansion of systemic options for advanced cases.

Indexed as

Thyroid NeoplasmsFemaleGermanyHumansIncidenceMalePrevalenceRisk FactorsSex DistributionSurvival Rate

Identifiers

PMID42015857
PMCPMC13484542

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.