Evidence map›Paper›PMID 42015784›Full record

ArticleJournal of traditional Chinese medicine = Chung i tsa chih ying wen pan2026

Characterizing the distribution of Chinese medicine syndrome of cancer-related fatigue in childhood lymphoma based on latent structure model.

Dong Ziqi, Huang Jing, L U Lu, Chen Yuru, Gan Guoling, Duan Yanlong, Jin Ling, Huang Shuang, Zhang Meng, L I Nan and 2 more

Abstract read
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Article in Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

12 authors.

Dong ZiqiDepartment of Pediatrics,Beijing Pinggu District Hospital of Traditional Chinese Medicine,BeiJing101200,China.
Huang JingDepartment of Pediatrics,Xiyuan Hospital, China Academy of Chinese Medical Sciences,BeiJing100091,China.
L U LuDepartment of pediatrics,Beijing Mentougou Maternaland Child Care Hospital,Beijing102300,China.
Chen YuruDepartment of Pediatrics,Dongzhimen Hospital, Beijing University of Chinese Medicine,Beijing100027,China.
Gan GuolingDepartment of Pediatrics,Dongzhimen Hospital, Beijing University of Chinese Medicine,Beijing100027,China.
Duan YanlongMedical Oncology Department,Pediatric Oncology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health,Beijing100045,China.
Jin LingMedical Oncology Department,Pediatric Oncology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health,Beijing100045,China.
Huang ShuangMedical Oncology Department,Pediatric Oncology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health,Beijing100045,China.
Zhang MengMedical Oncology Department,Pediatric Oncology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health,Beijing100045,China.
L I NanMedical Oncology Department,Pediatric Oncology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health,Beijing100045,China.
Gao ZhenDepartment of Pediatrics,Dongzhimen Hospital, Beijing University of Chinese Medicine,Beijing100027,China.
Lü JiaxuanDepartment of Pediatrics,Xiyuan Hospital, China Academy of Chinese Medical Sciences,BeiJing100091,China.

Funding

Establishment and Application of a Standardized Diagnosis and Treatment System for Pediatric Lymphoma XTZD20180204Preliminary Study on Tiered Healthcare Based on a Pediatric Collaborative Development Model XTGL201914
6 · The paper itself

Abstract

objectiveTo explore the distribution patterns of Traditional Chinese Medicine (TCM) syndromes in children with lymphoma-related cancer-related fatigue (CRF) using latent structure model analysis.

methodsThis was a single-center cross-sectional study in which Chinese medicine diagnostic information was collected from 153 children diagnosed with childhood lymphoma CRF from July 2022 to December 2023. The latent structure model of the CRF for childhood lymphoma was constructed using the latent tree model-extension adjustment simplification until termination algorithm, and the population was classified using comprehensive clustering. Combined with the existing guidelines, we explored the distribution characteristics and dynamic progression of syndrome types in patients with childhood lymphoma CRF.

resultsInitially, a latent structural model incorporating 72 manifest variables was constructed. Through comprehensive clustering, 6 distinct TCM syndrome types were identified, and corresponding quantitative identification rules were formulated. The 153 pediatric cases were then reclassified according to these rules, with the syndromes ranked in descending order of percentage as follows: blood deficiency and stasis, vigorous fire due to

conclusionUsing latent structure analysis, 6 TCM syndromes and their quantitative identification rules were identified. A comparison with existing guidelines revealed that CRF in patients with childhood lymphoma is characterized primarily by a syndrome of mixed deficiency and excess. Therefore, in the treatment of pediatric CRF, it is recommended not only that deficiency patterns be addressed but also that the clinical stage and treatment phase of the tumor be considered. Additionally, therapeutic strategies should emphasize promoting digestion, resolving food stagnation, regulating

Indexed as

FatigueLymphomaMedicine, Chinese TraditionalAdolescentChildChild, PreschoolCross-Sectional StudiesFemaleHumansMalecancer-related fatiguechildlymphomamodels, structuralsyndrome complex

Identifiers

PMID42015784
PMCPMC13077115

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