Evidence map›Paper›PMID 42015731›Full record

ArticleCancer science2026

Autophagy Inhibition by Fangji Huangqi Decoction Enhances Tumor Immunogenicity and Potentiates PD-1 Blockade.

Yuxiao Jiang, Shiji Zeng, Dingye Wang, Junbo Jiang, Zhenzhen Li, Jingbi Li, Dan Chen, Xu Zhao, Zheng Ying, Yuehua Deng and 9 more

Abstract read
In one paragraph

Article in Cancer science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Yuxiao JiangResearch Center of Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China.
Shiji ZengResearch Center of Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China.
Dingye WangResearch Center of Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China.
Junbo JiangResearch Center of Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China.
Zhenzhen LiZhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Chinese Medicine, Zhongshan, China.
Jingbi LiZhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Chinese Medicine, Zhongshan, China.
Dan ChenResearch Center of Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China.
Xu ZhaoResearch Center of Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China.
Zheng YingResearch Center of Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China.
Yuehua DengResearch Center of Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China.
Qianwei CaiResearch Center of Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China.
Silin MaiResearch Center of Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China.
Jiayi ZhengResearch Center of Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China.
Qiaohong YangDepartment of Pathology and Pathophysiology, Guangzhou University of Chinese Medicine, Guangzhou, China.
Fang LiuSchool of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China.
Biaoyan DuResearch Center of Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China.
Jianyong XiaoDepartment of Biochemistry, Guangzhou University of Chinese Medicine, Guangzhou, China.
Xiaoyi LiuDepartment of Human Anatomy, Guangzhou University of Chinese Medicine, Guangzhou, China.
Kun WangResearch Center of Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China.ORCID https://orcid.org/0000-0003-3282-4330

Funding

National Natural Science Foundation of China 82104571National Natural Science Foundation of China 82304938National Natural Science Foundation of China 82574775Natural Science Foundation of Guangdong Province 2022A1515110282Natural Science Foundation of Guangdong Province 2025A1515012216Natural Science Foundation of Guangdong Province 2025A1515012841Science and Technology Plan Project of Guangzhou, China 2023A04J2477Science and Technology Plan Project of Guangzhou, China 2024A04J10028the Research Special Fund for the High-Level Hospital Co-Construction Project between Guangzhou University of Chinese Medicine and Zhongshan Traditional Chinese Medicine Hospital GZYZS2024G01
6 · The paper itself

Abstract

Fangji Huangqi Decoction (FJHQ), a traditional Chinese medicine formula derived from "Jin Gui Yao Lue," has been reported to exhibit immunomodulatory and anti-inflammatory effects. This study investigates its potential anti-tumor mechanism via the enhancement of CD8

Indexed as

Carcinoma, Lewis LungDrugs, Chinese HerbalImmune Checkpoint InhibitorsImmunomodulating AgentsMelanoma, ExperimentalA549 CellsAnimalsAntigen PresentationAntineoplastic Combined Chemotherapy ProtocolsAutophagyCD8-Positive T-LymphocytesDrug SynergismGene Expression Regulation, NeoplasticGranzymesHistocompatibility Antigens Class IHumansDrugs, Chinese HerbalGranzymesHistocompatibility Antigens Class Ihuangqi decoctionImmune Checkpoint InhibitorsImmunomodulating AgentsInterferon-gammaProgrammed Cell Death 1 Receptorautophagy inhibitionCD8+ T cellsFangji Huangqi DecoctionMHC‐I antigen presentationPD‐1 blockadetumor immunity

Identifiers

PMID42015731
PMCPMC13327012

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.