Evidence map›Paper›PMID 42015711›Full record

ReviewZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2026

[Advances in the role of miR-378a in skeletal muscle development and diseases].

Zi-Ting Ding, Dan Lan

Abstract readReviewEnglish Abstract
In one paragraph

Review in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Zi-Ting DingDepartment of Pediatrics (Ward 3), First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Dan LanDepartment of Pediatrics (Ward 3), First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs) are endogenous noncoding RNAs involved in post-transcriptional regulation. miR-378a is highly expressed in skeletal muscle and plays important roles in myogenesis, maintenance of muscle homeostasis, and disease progression. Studies indicate that miR-378a participates in myogenic differentiation, energy metabolism, and muscle fiber-type switching by regulating molecules such as histone deacetylase 4 and mitogen-activated protein kinase 1. Dysregulated miR-378a is associated with muscle diseases: in Duchenne muscular dystrophy, its expression level negatively correlates with disease severity, and overexpression can ameliorate disease phenotypes; in limb-girdle muscular dystrophy type 3, rhabdomyosarcoma, sarcopenia, and spinal muscular atrophy, its potential value as a biomarker or therapeutic target has attracted increasing attention. This review summarizes the molecular characteristics of miR-378a and its roles in skeletal muscle development and related diseases, providing a reference for clinical translation.

Indexed as

MicroRNAsMuscle DevelopmentMuscle, SkeletalMuscular DiseasesAnimalsHistone DeacetylasesHumansHistone DeacetylasesMicroRNAsMIRN378 microRNA, humanBiomarkermiR-378aMuscle diseaseSkeletal myogenesisTherapeutic target

Identifiers

PMID42015711
PMCPMC13108946

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.