Evidence map›Paper›PMID 42015656›Full record

Trial reportThe Clinical journal of pain2026

Efficacy and Safety of Dorsal Root Ganglion Pulse Radiofrequency Combined With Sympathetic Radiofrequency Ablation in the Treatment of Acute Herpetic Neuralgia.

Ping Xu, Mingqing Yu, Hanrui Fan, Yong Fei

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in The Clinical journal of pain, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ping XuDepartment of Anesthesiology and Pain, The Affiliated Hospital of Jiaxing University, Jiaxing, People's Republic of China.
Mingqing Yu
Hanrui Fan
Yong Fei

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo explore the efficacy and safety of pulsed radiofrequency combined with sympathetic radiofrequency ablation of dorsal root ganglion in the treatment of acute herpetic neuralgia.

methodsA total of 116 patients diagnosed with acute herpetic neuralgia were randomly assigned to 2 groups: a dorsal root ganglion pulsed radiofrequency group (group C) and a dorsal root ganglion pulsed radiofrequency combined with sympathetic radiofrequency ablation group (group H). The treatment effects were evaluated using the Numerical Rating Scale, the Pittsburgh Sleep Quality Index, the proportion of patients utilizing tramadol, and the Current Perception threshold detection. In addition, serum levels of galectin-3 and interleukin-6 were measured as objective biological indicators to assess the therapeutic efficacy. The incidence of postherpetic neuralgia (PHN) and any complications were recorded for both groups.

resultsData showed that compared with group C, the Numerical Rating Scale, Pittsburgh Sleep Quality Index score, the proportion of patients using tramadol, and serum Galectin-3 and Interleukin-6 levels were significantly decreased, and Current Perception Threshold was significantly increased in group H ( P <0.05). The incidence of PHN in group H was significantly lower than that in group C. No serious adverse reactions occurred in either of the 2 groups after treatment. DISCUSSION: Dorsal root ganglion pulsed radiofrequency combined with sympathetic radiofrequency ablation is more effective in the treatment of acute herpetic neuralgia. Compared with pulsed radiofrequency therapy alone, it provides patients with longer-lasting pain relief, reduces the incidence of PHN, and improves the quality of life.

Indexed as

Ganglia, SpinalNeuralgia, PostherpeticPulsed Radiofrequency TreatmentRadiofrequency AblationAgedCombined Modality TherapyFemaleHumansInterleukin-6MaleMiddle AgedPain MeasurementTreatment OutcomeInterleukin-6herpes zosterpostherpetic neuralgiapulsed radiofrequencysympathetic nerve

Identifiers

PMID42015656
PMCPMC13348835

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.