ArticleThe New phytologist2026
NPF2 is involved in intracellular pH regulation and ion balance in the diatom Phaeodactylum tricornutum.
Article in The New phytologist, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
Abstract
Cellular ion and pH homeostasis are crucial factors affecting and regulating metabolic reactions, protein stability, signalling and transport mechanisms. To balance intracellular ion concentrations, organisms need to constantly sense and respond to both the extracellular environment and cell compartments' requests. This fine-tuned system has been deeply studied in organisms, such as land plants and animals, but for diatoms, living in a highly variable environment, the key regulators of intracellular homeostasis have not yet been characterized. Previous results showed a pH response in the expression of the Phaeodactylum tricornutum NRT1/PTR Family transporter 2 (NPF2) gene, homologous to bacterial Proton-coupled Oligopeptide Transporters (POTs) involved in proton translocation across membranes. Here, the P. tricornutum NPF2 protein was shown to localize in the periplastidial compartment, between two of the four membranes of diatom chloroplasts, and to play a role in maintaining intracellular pH (pH
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.