Evidence map›Paper›PMID 42015462›Full record

ArticleTransfusion2026

Assessment of implementation of ferritin testing on donor return.

Mindy Goldman, Chinchin Wang, Aditi Khandelwal, Sheila F O'Brien

Abstract read
In one paragraph

Article in Transfusion, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mindy GoldmanCanadian Blood Services, Ottawa, Ontario, Canada.ORCID https://orcid.org/0000-0001-9904-9952
Chinchin WangCanadian Blood Services, Ottawa, Ontario, Canada.ORCID https://orcid.org/0000-0002-8472-9936
Aditi KhandelwalCanadian Blood Services, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-5585-6194
Sheila F O'BrienCanadian Blood Services, Ottawa, Ontario, Canada.ORCID https://orcid.org/0000-0002-5332-2789

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOne mitigation strategy for donor iron deficiency is to implement ferritin testing and encourage donors with low ferritin to pause donation and increase iron intake. We evaluated positive outcomes (reduced hemoglobin deferrals) and negative outcomes (donor nonreturn) in a 2-year observation period after implementing ferritin testing of female donors at each 10th donation.

methodsDonors with ferritin below 25 ug/L were advised to pause donation for 6 months and see their health care practitioner about increasing iron intake but were not deferred. Ferritin results for donors screened in the first 6 months of the program (Jan-June 2023), hemoglobin on return and time to return in the 2 years following testing were calculated for low ferritin and normal/high ferritin donors.

resultsTwenty five percent of 8613 tested donors had low ferritin, associated with younger age, high donation frequency, and previous hemoglobin deferral. About one third of low ferritin donors returned to donate less than 6 months after testing, and had a hemoglobin deferral rate of 16%, compared to 4.4% in those who waited 6 months or more and 5.2% in donors with normal ferritin. After 2 years, 77.5% of low ferritin compared to 88.5% of normal/high ferritin donors returned to donate.

conclusionIron deficiency was common. Low ferritin donors who paused donation and returned to donate had hemoglobin deferral rates similar to normal ferritin donors. However, many returned early and had high failure rates. Two years after testing, an 11% difference in return rates remained between low and normal/high ferritin donors.

Indexed as

Blood DonorsFerritinsAdultBlood DonationFemaleHemoglobinsHumansIronMaleMiddle AgedFerritinsHemoglobinsIrondonor behaviordonorshemoglobiniron

Identifiers

PMID42015462
PMCPMC13350547

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.