Evidence map›Paper›PMID 42015408›Full record

ArticleParasites, hosts and diseases2026

Therapeutic efficacy of an ivermectin dose of 200 μg/kg/day for 2 consecutive days to treat Strongyloides stercoralis infection: A serological evaluation in Vietnam.

Van Hue Thi Tran, Chinh Duc Nguyen, Quang Hong Huynh

Abstract read
In one paragraph

Article in Parasites, hosts and diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Van Hue Thi TranDepartment of Microbiology and Parasitology, School of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Chinh Duc NguyenDepartment of Microbiology and Parasitology, School of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Quang Hong HuynhInstitute of Malariology, Parasitology and Entomology Quy Nhon (IMPEQN), Quy Nhon City, Vietnam.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Strongyloidiasis is a neglected infectious disease with diverse clinical manifestations that may lead to severe complications, including death in immunocompromised individuals. Uncomplicated infections can be diagnosed early using serological testing. Regarding treatment, the World Health Organization recommends ivermectin, thiabendazole, and albendazole as effective therapies against Strongyloides stercoralis. The objective of this study was to evaluate the therapeutic effectiveness of ivermectin 200 μg/kg/day for 2 consecutive days in patients infected with S. stercoralis, with the aim of optimizing treatment efficacy while shortening the duration of therapy compared with longer regimens. This before-and-after study assessed the therapeutic effectiveness of ivermectin 200 μg/kg/day for 2 consecutive days in patients with S. stercoralis infection. From January to October 2023, 3,814 patients with suspected S. stercoralis infection-presenting with symptoms such as urticaria, abdominal pain, and loose stools with seropositivity on an enzyme-linked immunosorbent assay for IgG antibodies against S. stercoralis-were screened, and 42 patients with uncomplicated S. stercoralis mono-infection were recruited. Symptoms, IgG optical density antibody titers against S. stercoralis, and eosinophils were assessed before and after treatment. Therapeutic effectiveness was evaluated based on cure rate and disease reduction after intervention. After 3 months of treatment, the overall effectiveness of ivermectin 200 μg/kg/day for 2 consecutive days reached 95.2%, of which 50% were completely cured, 9.5% had symptom resolution without improvement in paraclinical indicators, 21.4% experienced clear symptom reduction, and 14.3% had symptom recurrence. The regimen of ivermectin 200 μg/kg/day for 2 consecutive days demonstrated high effectiveness in the treatment of strongyloidiasis.

Indexed as

AnthelminticsIvermectinStrongyloides stercoralisStrongyloidiasisAdolescentAdultAgedAnimalsAntibodies, HelminthFemaleHumansImmunoglobulin GMaleMiddle AgedTreatment OutcomeVietnamAnthelminticsAntibodies, HelminthImmunoglobulin GIvermectinivermectinStrongyloides stercoralisstrongyloidiasis

Identifiers

PMID42015408
PMCPMC13485479

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.