Evidence map›Paper›PMID 42015366›Full record

ReviewMini reviews in medicinal chemistry2026

The Multifaceted Potential of

Sekhar Tiwari, Priyanka Panchal, Harsh Mehta, Sabir Khan Pathan, Sujeet Kumar Mritunjay, Aryaman Singh, Cecileya Jasmin Meshak Dhanashekaran, Vinod Prabhu Venugopal

Abstract readReview
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In one paragraph

Review in Mini reviews in medicinal chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sekhar TiwariDepartment of Microbiology, School of Sciences, P P Savani University, Kosamba, Surat, 394125, Gujarat, India.
Priyanka PanchalDepartment of Microbiology, School of Sciences, P P Savani University, Kosamba, Surat, 394125, Gujarat, India.
Harsh MehtaDepartment of Microbiology, School of Sciences, P P Savani University, Kosamba, Surat, 394125, Gujarat, India.
Sabir Khan PathanDepartment of Microbiology, School of Sciences, P P Savani University, Kosamba, Surat, 394125, Gujarat, India.
Sujeet Kumar MritunjayDepartment of Microbiology, School of Sciences, P P Savani University, Kosamba, Surat, 394125, Gujarat, India.
Aryaman SinghDatum Laboratories, GIDC, Ankleshwar, 393001, Gujarat, India.
Cecileya Jasmin Meshak DhanashekaranDepartment of Microbiology, School of Sciences, P P Savani University, Kosamba, Surat, 394125, Gujarat, India.
Vinod Prabhu VenugopalDepartment of Microbiology, School of Sciences, P P Savani University, Kosamba, Surat, 394125, Gujarat, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adhatoda vasica Nees (A. vasica), known as the Malabar nut, belongs to the Acanthaceae family and is widely distributed across South and Southeast Asia. It is used in Ayurveda and Unani medicine as a therapy for human diseases, such as respiratory ailments like asthma, bronchitis, and tuberculosis. These plants are reported to be rich in alkaloids, flavonoids, tannins, and saponins, with vasicine and vasicinone as the primary bioactive compounds for their therapeutic activity. A. vasica has also been identified to contain several secondary metabolites, such as quercetin, kaempferol, and apigenin, that exhibit antioxidant, antimicrobial, anti-inflammatory, and immunomodulatory activities. The transcriptome analysis of A. vasica identified 171,064 transcripts corresponding to 55,528 genes, which are associated with key biosynthetic pathways. Therefore, these A. vasica were overharvested, precisely because of their widespread medicinal use and habitat destruction, and have been placed in the threatened species category in India. This review will emphasize the need for sustainable cultivation practices and biotechnological applications in order to preserve its availability for its therapeutic benefits. Moreover, clinical trials are necessary to validate its effectiveness and safety for its therapeutic applications. Integrating traditional knowledge with modern biotechnological advancements, the A. vasica plant could be a potential contributor to the pharmaceutical industry, developing new drugs with little or no adverse effects that can improve the quality of life of patients during treatment.

Indexed as

BiotechnologyJusticiaPlant ExtractsAnimalsAnti-Infective AgentsAnti-Inflammatory AgentsAntioxidantsHumansAnti-Infective AgentsAnti-Inflammatory AgentsAntioxidantsPlant ExtractsAdhatoda vasicaalkaloidsanti-cancerayurvedamedicinal plantsphytochemistryvasicine

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.