Evidence map›Paper›PMID 42015123›Full record

ArticleBMC ophthalmology2026

Demographic and clinical presentations of keratoconus in Trinidad and Tobago: a retrospective study.

Ngozika Esther Ezinne, Michael Agyemang Kwarteng, Selassie Tagoh, Elicia Bissoon, Destiny Lawrence, Uchechukwu Levi Osuagwu

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Article in BMC ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Ngozika Esther EzinneOptometry Unit, Department of Clinical Surgical Sciences, University of the West Indies, Saint Augustine Campus, St Augustine, Trinidad and Tobago.
Michael Agyemang KwartengOptometry Unit, Department of Clinical Surgical Sciences, University of the West Indies, Saint Augustine Campus, St Augustine, Trinidad and Tobago.
Selassie TagohDepartment of Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand.
Elicia BissoonOptometry Unit, Department of Clinical Surgical Sciences, University of the West Indies, Saint Augustine Campus, St Augustine, Trinidad and Tobago.
Destiny LawrenceOptometry Unit, Department of Clinical Surgical Sciences, University of the West Indies, Saint Augustine Campus, St Augustine, Trinidad and Tobago.
Uchechukwu Levi OsuagwuBathurst Rural Clinical School (BRCS), School of Medicine, Faculty of Health, Western Sydney University, Bathurst, NSW, Australia. l.osuagwu@westernsydney.edu.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKeratoconus is a progressive corneal disorder characterised by thinning and protrusion of the cornea, leading to irregular astigmatism and visual impairment. Data describing the demographic and clinical profiles of Caribbean populations are limited. This study evaluated the demographic and clinical characteristics of keratoconus among patients in Trinidad and Tobago.

methodA retrospective chart review was conducted among patients diagnosed with keratoconus who attended the University of the West Indies Optometry Clinic in Trinidad and Tobago between January 2010 and December 2022. Data collected included demographics, clinical signs, visual acuity, keratometry, pachymetry, refractive error, and known risk factors (family history, history of allergy, dry eye, and systemic diseases). Diagnosis of keratoconus was based on a combination of clinical signs and imaging findings, and severity was graded using the Amsler-Krumeich classification. Descriptive analysis and chi-square tests were performed to assess associations between variables.

resultsThere was a total of 189 participants, most of who were aged 21–30 years (38.6%, n = 73), females (53.4%, n = 101), had Indian background (50.8%, n = 96), and many lived in the urban areas (91%, n = 172). Eye rubbing was reported in 45.5% (n = 86) and was significantly associated with ethnicity (p = 0.047) and occupation (p = 0.027). Advanced keratoconus (K > 55D) was present in ~ 30% of eyes. Common signs included Munson’s sign (27%, n = 44), Vogt’s striae (23%, n = 21), and Fleischer’s ring (19%, n = 35). Treatments included corneal cross-linking (24.3%, n = 47), glasses (13.8%, n = 27), and scleral lenses (11.6%, n = 21). Mean visual acuity improved post-treatment (mean LogMAR: right eye from 0.53 to 0.29; left eye from 0.51 to 0.30).

conclusionThis study provides the first comprehensive profile of keratoconus in Trinidad and Tobago, revealing a predominance among young adults of Indian descent and a substantial number of advanced cases at diagnosis. These findings highlight the need for early detection strategies, public education, and improved access to diagnostic and therapeutic interventions in the region.

Indexed as

CorneaKeratoconusAdolescentAdultAge DistributionCorneal PachymetryCorneal TopographyFemaleHumansMaleMiddle AgedRetrospective StudiesRisk FactorsSex DistributionTrinidad and TobagoVisual AcuityCaribbeanClinical presentationsDemographyDisease stageKeratoconusTrinidad and Tobago

Identifiers

PMID42015123
PMCPMC13235144

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