Evidence map›Paper›PMID 42015066›Full record

ArticleBMC gastroenterology2026

Impact of surgical delay on bowel viability in internal hernia-related small bowel obstructon: a retrospective cohort study of clinical, imaging, and biochemical predictors of strangulation.

Judong Zhang, Yifang Hsieh, Longchun Dong, Jing Xu

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Article in BMC gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Judong Zhang *Department of General Surgery, Tianjin Union Medical Center, The First Affiliated Hospital of Nankai University, Tianjin, 300121, China.
Yifang Hsieh *Department of General Surgery, Tianjin Union Medical Center, The First Affiliated Hospital of Nankai University, Tianjin, 300121, China.
Longchun DongDepartment of Radiology, Tianjin Union Medical Center, The First Affiliated Hospital of Nankai University, Tianjin, 300121, China.
Jing XuDepartment of General Surgery, Tianjin Union Medical Center, The First Affiliated Hospital of Nankai University, Tianjin, 300121, China. xujingdoc@126.com.ORCID http://orcid.org/0000-0001-7126-1652

Funding

National Engineering Research Center of Science and Technology Information STI Digital Health Laboratory (Beijing Zhilian Research Institute for Innovation and Digital Health) 2025STI81Natural Science Foundation of Tianjin 24JCZDJC01350Tianjin Key Medical Discipline Construction Project TJYXZDXK-3-009B
6 · The paper itself

Abstract

backgroundInternal hernia–related small bowel obstruction (SBO) is a time-critical condition that may rapidly progress to strangulation and bowel necrosis. Early surgical decision-making is challenging because classical clinical and radiological signs of ischemia are often absent during the reversible phase. This study aimed to identify clinical, imaging, and biochemical factors associated with bowel strangulation and delayed surgical intervention in patients with internal hernia–related SBO.

methodsThis retrospective cohort study included patients who underwent surgery for internal hernia–related SBO between January 2019 and December 2025. Admission laboratory parameters and preoperative non-enhanced abdominal computed tomography (CT) findings were analyzed. Multivariable logistic regression was used to identify predictors of bowel strangulation and factors associated with delayed surgical intervention. Clinical outcomes were compared between delayed and non-delayed surgery groups.

resultsA total of 119 patients were included, of whom 82 (68.9%) had strangulated internal hernia. Lactate (OR = 3.975) and D-dimer (OR = 3.412) were independent predictors of bowel strangulation. In patients with strangulated internal hernia, the absence of peritonitis (OR = 0.021), absence of the whirlpool sign on CT (OR = 0.147), and higher base excess (OR = 1.274) were independently associated with delayed surgical intervention. Patients in the delayed surgery group had significantly higher rates of bowel resection (85.7% vs. 53.2%), bowel necrosis, and longer hospital stays compared with those undergoing timely surgery.

conclusionSurgical delay in internal hernia–related SBO is frequently driven by deceptively mild clinical and radiological findings during early ischemia. While lactate and D-dimer indicate established strangulation, base excess—together with non-enhanced CT features—may provide earlier warning of mesenteric compromise. An integrated interpretation of laboratory and imaging findings may facilitate earlier surgical intervention, reduce bowel resection, and improve clinical outcomes.

Indexed as

Internal HerniaIntestinal ObstructionIntestine, SmallTime-to-TreatmentAgedFemaleFibrin Fibrinogen Degradation ProductsHumansLactic AcidMaleMiddle AgedNecrosisRetrospective StudiesTomography, X-Ray ComputedTreatment DelayFibrin Fibrinogen Degradation ProductsLactic AcidBase excessComputed tomographyInternal herniaSmall bowel obstructionStrangulation

Identifiers

PMID42015066
PMCPMC13214441

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.