ArticleInquiry : a journal of medical care organization, provision and financing
Prevalence of Multidrug-Resistant Organisms During Hospitalization and Its Association with Patient's Functional Status at Discharge: A Retrospective Cohort Study.
Article in Inquiry : a journal of medical care organization, provision and financing. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
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Abstract
Multidrug-resistant organisms (MDROs) represent a growing global threat due to resistance to multiple antibiotics, limited treatment options, longer hospitalizations, higher costs, and increased mortality. Although the clinical impact of MDROs is well recognized, their effect on patients' functional recovery remains understudied. This study aimed to determine the prevalence of MDRO infections across hospital settings and examine their association with changes in functional status. A retrospective cohort study analyzed 30 428 adult hospitalizations from 2020 to 2023 in a 294-bed hospital in northern Italy. Demographic data, hospitalization characteristics, MDRO status, and Barthel Index scores at admission and discharge were collected. A multilevel linear regression model examined the effect of MDRO infection on Barthel variation, adjusting for age, sex, discharge area, and length of stay. MDRO infections occurred in 2.4% of hospitalizations (n = 732), mainly in medical and surgical wards, with the highest prevalence in medical and rehabilitation areas. The most common pathogens were ESBL-producing Enterobacteriaceae and vancomycin-resistant enterococci. Patients without MDRO infection showed greater improvement in Barthel scores than those with infection (+3.081;
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