Evidence map›Paper›PMID 42014842›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2026

Macronutrient and bioactive profiles of donor milk differ in commercial vs non-profit milk banks.

Tanner Tarkleson, Danielle Ackley, Laura Cole, Manisha Srivastava, Lori Scholer, Carrie Gale, Jeffrey Meyers, Carl D' Angio, Bridget Young

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Tanner TarklesonUniversity of Rochester School of Medicine and Dentistry, Rochester, NY, USA. Tanner_Tarkleson@URMC.Rochester.edu.ORCID http://orcid.org/0009-0004-2382-5977
Danielle AckleyDepartment of Pediatrics - Neonatology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.ORCID http://orcid.org/0000-0001-7461-5938
Laura ColeDepartment of Pediatrics - Breastfeeding and Lactation Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.
Manisha SrivastavaDepartment of Pediatrics - Neonatology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.
Lori ScholerDepartment of Pediatrics - Neonatology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.
Carrie GaleDepartment of Pediatrics - Neonatology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.
Jeffrey MeyersDepartment of Pediatrics - Neonatology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.ORCID http://orcid.org/0009-0004-6061-8635
Carl D' AngioDepartment of Pediatrics - Neonatology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.
Bridget YoungDepartment of Pediatrics - Breastfeeding and Lactation Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.ORCID http://orcid.org/0000-0002-3257-8179

Funding

The University of Rochester's Clinical and Translational Science InstituteUL1TR002001 · NCATS · UNIVERSITY OF ROCHESTER · PI WILSON, KAREN M., ZAND, MARTIN S · 2016 to 2024
$34.6M
Developmental Infant Effects of Exposure to High Doses of Oral Insulin in Human Milk (HM)R03DK131219 · NIDDK · UNIVERSITY OF ROCHESTER · PI YOUNG, BRIDGET VICTORIA · 2022 to 2023
$231k
NCATS NIH HHS UL1 TR002001NIDDK NIH HHS R03 DK131219U.S. Department of Health & Human Services | NIH | National Center for Advancing Translational Sciences (NCATS) UL1 TR002001U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (National Institute of Diabetes & Digestive & Kidney Diseases) R03 DK131219
6 · The paper itself

Abstract

objectiveCharacterize variation of macronutrient and bioactive composition between levels of human milk-derived human milk fortifier (HM-HMF), and between donor human milk (DHM) from commercial vs non-profit banks. STUDY

designMacronutrients, Immunoglobulin A (IgA), and cortisol levels were measured in 10 lots of each HM-HMF product (20, 24, 26, 28, and 30 (n = 5) kcal/oz), including both "ready to feed" products and fortifiers reconstituted in donor milk.

resultsCaloric density, protein, fat, carbohydrate, and total IgA concentration generally increased with the level of HM-HMF labeled caloric density, while cortisol concentration did not. Protein concentration of DHM did not differ between commercial and non-profit milk banks. Carbohydrates, fat, calories, and cortisol were higher, and IgA was lower in DHM from a commercial milk bank. Lot-to-lot variability of all components, besides cortisol, was lower in commercial DHM.

conclusionMacronutrient composition and variability differ in DHM from commercial vs non-profit milk banks.

Indexed as

Food, FortifiedMilk BanksMilk, HumanNutrientsOrganizations, NonprofitFemaleHumansHydrocortisoneImmunoglobulin AHydrocortisoneImmunoglobulin A

Identifiers

PMID42014842

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.