Evidence map›Paper›PMID 42014841›Full record

Observational studyJournal of perinatology : official journal of the California Perinatal Association2026

Feasibility of invasive neurally-adjusted ventilatory assist in severe congenital diaphragmatic hernia.

Joo Hyung Roh, Euiseok Jung, Juhee Park, Kyusang Yoo, Abraham Kwak, Tae-Gyeong Kim, Jung Il Kwak, Jeong Min Lee, Ha Na Lee, Ji Yoon Jeong and 3 more

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Joo Hyung RohDivision of Neonatology, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Republic of Korea.ORCID http://orcid.org/0009-0006-7965-4980
Euiseok JungDivision of Neonatology, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Republic of Korea. euisjung@amc.seoul.kr.ORCID http://orcid.org/0000-0003-0693-5627
Juhee ParkDivision of Neonatology, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Kyusang YooDivision of Neonatology, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Republic of Korea.ORCID http://orcid.org/0009-0005-6952-961X
Abraham KwakDivision of Neonatology, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0002-8161-333X
Tae-Gyeong KimDivision of Neonatology, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Jung Il KwakDivision of Neonatology, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Jeong Min LeeDivision of Neonatology, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Ha Na LeeDivision of Neonatology, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0002-0217-1773
Ji Yoon JeongDivision of Neonatology, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Soo Hyun KimDivision of Neonatology, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Chae Young KimDivision of Neonatology, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Byong Sop LeeDivision of Neonatology, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the feasibility and early physiologic effects of postoperative invasive neurally-adjusted ventilatory assist (NAVA) in neonates with severe congenital diaphragmatic hernia (CDH). STUDY

designRetrospective observational study of inborn neonates with CDH who received invasive NAVA during the post-repair ventilator weaning phase. Ventilator parameters, blood gas variables, respiratory indices, and diaphragm-based efficiency measures were evaluated serially within infants at 0, 12, 24, and 48 hours after NAVA initiation.

resultsOf 123 inborn infants with CDH, 19 with high disease severity received postoperative invasive NAVA. Oxygen requirements decreased over time, with favorable changes in gas exchange by 48 hours. The oxygenation index declined without increased ventilator pressures. Neuroventilatory and neuromechanical efficiency remained stable, including in infants with type D defects. All infants were successfully weaned from invasive mechanical ventilation.

conclusionsPostoperative invasive NAVA was feasible and well tolerated in neonates with severe CDH, including those with type D defects and prior extracorporeal membrane oxygenation support.

Indexed as

Hernias, Diaphragmatic, CongenitalInteractive Ventilatory SupportFeasibility StudiesFemaleHumansInfant, NewbornMaleRetrospective StudiesSeverity of Illness IndexTreatment OutcomeVentilator Weaning

Identifiers

PMID42014841

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.