Evidence map›Paper›PMID 42013849›Full record

ArticleCell reports. Medicine2026

Plasma extracellular vesicle proteomics nominates candidate biomarkers of

Ali T Arafa, Ella Boytim, Megan L Ludwig, Lily Kollitz, Tianzhong Yang, Kathleen M Storey, Stuart Bloom, Gautam Jha, Ian Okazaki, Charles J Ryan and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell reports. Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Ali T ArafaDepartment of Pharmacology, University of Minnesota, Minneapolis, MN 55455, USA.
Ella BoytimDivision of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.
Megan L LudwigDepartment of Pharmacology, University of Minnesota, Minneapolis, MN 55455, USA.
Lily KollitzNuclear Medicine Division, Department of Radiology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Tianzhong YangDivision of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, Minneapolis, MN, USA.
Kathleen M StoreyDivision of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.
Stuart BloomDivision of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.
Gautam JhaDivision of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.
Ian OkazakiDivision of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.
Charles J RyanMemorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Nicholas A ZorkoDivision of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.
Daniel SteinbergerNuclear Medicine Division, Department of Radiology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Zuzan CayciNuclear Medicine Division, Department of Radiology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Yingchun ZhaoMasonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.
Peter W VillaltaMasonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA; Department of Medicinal Chemistry, University of Minnesota, Minneapolis, MN 55455, USA.
Scott M DehmMasonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN 55455, USA; Department of Urology, University of Minnesota, Minneapolis, MN 55455, USA.
Justin H HwangDivision of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.
Justin M DrakeDepartment of Pharmacology, University of Minnesota, Minneapolis, MN 55455, USA; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA; Department of Urology, University of Minnesota, Minneapolis, MN 55455, USA; Astrin Biosciences, Saint Paul, MN 55114, USA. Electronic address: jdrake@umn.edu.
Emmanuel S AntonarakisDivision of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA. Electronic address: anton401@umn.edu.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Dissecting mechanisms of sensitivity to B7-H3 (CD276)-targeted therapeutics in prostate cancer (PC)R37CA288972 · NCI · UNIVERSITY OF MINNESOTA · PI Justin H. Hwang · 2024 to 2026
$1.1M
NCI NIH HHS P30 CA008748NCI NIH HHS R37 CA288972
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Biomarkers, TumorDipeptidesExtracellular VesiclesHeterocyclic Compounds, 1-RingLutetiumProstatic Neoplasms, Castration-ResistantProteomicsAgedAntigens, NeoplasmAntigens, SurfaceHumansMaleMiddle AgedNeoplasm MetastasisOxidoreductasesProstate-Specific AntigenAntigens, NeoplasmAntigens, SurfaceBiomarkers, TumorDipeptidesHeterocyclic Compounds, 1-RingLutetiumOxidoreductasesProstate-Specific AntigenPSMA-617RadioisotopesSTEAP1 protein, human(177)Lu-PSMA-617B7-H3castration-resistant prostate cancerextracellular vesiclesliquid biopsyplasma proteomicsPSMAshotgun proteomicsSTEAP1Trop-2

Identifiers

PMID42013849
PMCPMC13198300

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.