Evidence map›Paper›PMID 42013188›Full record

ArticleCirculation. Heart failure2026

Center and Geographic Variability in Acceptance of the First Donor Heart by Race.

Khadijah Breathett, Shannon M Knapp, Edward J Bedrick, Ryan J Tedford, Shannon M Dunlay, Selma F Mohammed, Monica M Colvin, Richard Daly

Abstract read
In one paragraph

Article in Circulation. Heart failure, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Khadijah BreathettDivision of Cardiovascular Medicine, Krannert Cardiovascular Research Center, Indiana University, Indianapolis (K.B., S.M.K.).ORCID 0000-0001-5397-6419
Shannon M KnappDivision of Cardiovascular Medicine, Krannert Cardiovascular Research Center, Indiana University, Indianapolis (K.B., S.M.K.).ORCID 0000-0002-9017-7007
Edward J BedrickDepartment of Epidemiology and Biostatistics, University of Arizona, Tucson (E.J.B.).ORCID 0000-0002-4215-795X
Ryan J TedfordDivision of Cardiovascular Medicine, Medical University of South Carolina, Charleston (R.J.T.).ORCID 0000-0001-9045-7722
Shannon M DunlayDepartment of Cardiovascular Medicine (S.M.D.), Mayo Clinic, Rochester, MN.ORCID 0000-0001-5145-7420
Selma F MohammedDepartment of Public Health Division of Cardiovascular Medicine, Creighton University, Omaha, NE (S.F.M.).ORCID 0000-0003-3553-2720
Monica M ColvinDivision of Cardiovascular Medicine, University of Michigan, Ann Arbor (M.C.C.).ORCID 0000-0001-9294-4612
Richard DalyDepartment of Cardiothoracic Surgery (R.D.), Mayo Clinic, Rochester, MN.ORCID 0009-0005-4266-0722

Funding

Seeking Objectivity in Allocation of Advanced Heart Failure (SOCIAL HF) Therapies TrialR01HL159216 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI BREATHETT, KHADIJAH · 2022 to 2025
$2.6M
NHLBI NIH HHS R01 HL159216
6 · The paper itself

Abstract

backgroundAmong accepted US heart organs, listing centers accept organ offers earliest for White women, followed by Black women, White men, and Black men. Understanding the relationships of center- and geographic-level decisions is necessary to understand waitlist disparities. We sought to determine whether listing center and geography are associated with the first heart organ acceptance by candidate race, since race demographics vary regionally across the United States.

methodsUsing the United Network for Organ Sharing data sets, we identified first organ offers for Black and White candidates listed for heart transplant (October 18, 2018 to September 30, 2024) and compared models with and without listing center effects adjusted for candidate-, donor-, and offer-level variables.

resultsAmong 20 668 candidates (31.6% Black, 68.4% White, 26.5% women), the adjusted odds of first offer acceptance were lower for Black candidates compared with White candidates (odds ratio, 0.84 [95% CI, 0.76-0.94];

conclusionsVariability in overall acceptance rate among listing centers explains the lower first offer acceptance for Black compared with White heart candidates. Baseline acceptance rates were linked to the center-level proportion of Black candidates but not geography. Investigation of strategies to systemically improve early acceptance of good heart organs may reduce Black and White disparities in wait time duration.

Indexed as

Healthcare DisparitiesHeart TransplantationRacial GroupsTissue and Organ ProcurementTissue DonorsWaiting ListsAdultBlack or African AmericanFemaleHumansMaleMiddle AgedUnited StatesWhitehealthcare disparitiesheart transplantationorgan donortransplant recipientswaiting list

Identifiers

PMID42013188
PMCPMC13095063

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.