Article in Science signaling, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Erica L SchellerDivision of Bone and Mineral Diseases, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0002-1551-3816
Deborah J VeisDivision of Bone and Mineral Diseases, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0001-7101-5582
Yousef Abu-AmerDepartment of Orthopedic Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0002-5890-5086
Roberta FaccioDepartment of Orthopedic Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0003-1639-2005
Gabriel MbalavieleDivision of Bone and Mineral Diseases, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0003-4660-0952
Funding
DIABETES &RELATED METABOLIC DISEASEST32DK007120 · NIDDK · WASHINGTON UNIVERSITY · PI MARCO COLONNA, Maria Sara Remedi · 1986 to 2026
$15.7M
Resource Based Center for Musculoskeletal Biology and Medicine (Overall Application)P30AR074992 · NIAMS · WASHINGTON UNIVERSITY · PI MATTHEW J SILVA · 2019 to 2026
$6.8M
Skeletal Disorders Training ProgramT32AR060719 · NIAMS · WASHINGTON UNIVERSITY · PI Roberto Civitelli · 2011 to 2026
$4.6M
Differential Inflammasome Regulation in the pathogenesis of S. aureus osteomyelitisR01AI161022 · NIAID · WASHINGTON UNIVERSITY · PI CASSAT, JAMES E, MBALAVIELE, GABRIEL · 2021 to 2025
$3.4M
Molecular pathways of calcium pyrophosphate deposition diseaseR01AG077732 · NIA · MEDICAL COLLEGE OF WISCONSIN · PI Gabriel Mbalaviele, Ann K Rosenthal · 2022 to 2026
$2.4M
Regulation of Osteoclastogenesis and Inflammatory OsteolysisR01AR082192 · NIAMS · WASHINGTON UNIVERSITY · PI Yousef Abu-Amer · 2023 to 2026
$1.9M
Role of gasdermin D in bone resorptionR01AR076758 · NIAMS · WASHINGTON UNIVERSITY · PI MBALAVIELE, GABRIEL · 2020 to 2024
$1.9M
Novel insulin-sensitizing NASH/diabetes drugs.R42DK121652 · NIDDK · BIOIO, LLC · PI FINCK, BRIAN N, PETERSON, TIMOTHY R · 2019 to 2022
$1.7M
Mechanisms of Physiologic and Pathologic OsteoclastogenesisR01AR072623 · NIAMS · WASHINGTON UNIVERSITY · PI ABU-AMER, YOUSEF · 2018 to 2022
$1.7M
Sarm1 and neural regulation of boneR01DK132073 · NIDDK · WASHINGTON UNIVERSITY · PI Erica Lynn Scheller · 2023 to 2026
$1.6M
Cabinet microCT System for Musculoskeletal Specimen ImagingS10OD028573 · OD · WASHINGTON UNIVERSITY · PI SILVA, MATTHEW J · 2020 to 2020
$407k
Drug target identification using CRISPRi/a screeningR41GM137625 · NIGMS · BIOIO, LLC · PI GILBERT, LUKE, PETERSON, TIMOTHY R · 2020 to 2020
Activation of the NLRP3 inflammasome can drive bone resorption by osteoclasts in various inflammatory conditions. Here, we identified Tmem178, a protein that restrains Ca
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Activation of the NLRP3 inflammasome in osteoclasts is suppressed by a Tmem178-dependent mechanism that restricts Ca · full record | OpenQuestion