Evidence map›Paper›PMID 42013163›Full record

ArticlePloS one2026

Clinical outcomes and associated factors among mechanically ventilated patients in adult intensive care unit at Jimma Medical Center, Southwest Ethiopia, 2024.

Abera Mulatu Uma, Shemsadin Ame, Segni Gemechu Hurisa, Mulu Kitaba Negawo, Sheka Shemsi Seid

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Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Abera Mulatu UmaDepartment of Emergency and Critical care Nursing, School of Nursing and Midwifery, College of Health Science and Referral hospital, Ambo University, Ambo, Ethiopia.ORCID https://orcid.org/0009-0002-0511-8625
Shemsadin AmeDepartment of Emergency and Critical care Nursing, School of Nursing, Institute of Health, Jimma University, Jimma, Ethiopia.
Segni Gemechu HurisaDepartment of Medical Physiology, School of Medicine, College of Health Science and Referral hospital, Ambo University, Ambo, Ethiopia.ORCID https://orcid.org/0009-0000-9695-9491
Mulu Kitaba NegawoDepartment Nursing, School of Nursing and Midwifery, College of Health Science and Referral hospital, Ambo University, Ambo, Ethiopia.ORCID https://orcid.org/0000-0002-1477-3405
Sheka Shemsi SeidDepartment of Emergency and Critical care Nursing, School of Nursing, Institute of Health, Jimma University, Jimma, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMechanical ventilation (MV) is a life‑saving intervention for patients unable to maintain adequate oxygenation or ventilation. However, MV is also associated with complications such as ventilator‑associated pneumonia, lung injury, and prolonged ICU stay, which may increase morbidity and mortality. Previous studies in Ethiopia and the region are limited and do not fully address key predictors of clinical outcomes among mechanically ventilated patients. Objective: To assess clinical outcomes and associated factors among mechanically ventilated patients in adult intensive care units at Jimma Medical Center, Southwest Ethiopia, and in2024.

methodsA retrospective cross‑sectional study was conducted among 411 randomly selected medical records of mechanically ventilated adult patients. Data were extracted using a structured and pretested tool. Statistical analysis included bivariable and multivariable logistic regression. Variables with p < 0.25 were entered into the multivariable model, and statistical significance was declared at p < 0.05. Adjusted Odds Ratios (AORs) with 95% Confidence Intervals (CIs) were reported.

resultsOf the 411 reviewed patient charts, 215 (52.3%) were male with a mean age of 36.9 ± 16.2 years. The overall mortality rate was 54% (95% CI: 49.4-58.6). Significant predictors of mortality included hospital stay > 5 days before intubation (AOR = 3.03, 95% CI: 1.05-6.09), re‑intubation (AOR = 9.02, 95% CI: 4.07-20.01), presence of comorbidities (AOR = 9.12, 95% CI: 4.38-18.99), development of complications (AOR = 6.84, 95% CI: 3.15-14.81), multi‑organ dysfunction syndrome (MODS) (AOR = 3.48, 95% CI: 1.47-7.82), and use of sedation (AOR = 0.36, 95% CI: 0.18-0.74).

conclusionMechanically ventilated patients at Jimma Medical Center experience a high mortality rate. Key determinants of mortality were re‑intubation, comorbidities, complications, MODS, and delayed intubation. Improving ICU protocols, early identification of high‑risk patients, proper monitoring, and prevention of unplanned extubation may improve survival outcomes.

Indexed as

Intensive Care UnitsRespiration, ArtificialAdultAgedCross-Sectional StudiesEthiopiaFemaleHospital MortalityHumansLength of StayMaleMiddle AgedRetrospective StudiesRisk FactorsTreatment OutcomeYoung Adult

Identifiers

PMID42013163
PMCPMC13098938

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.