ArticleCancer control : journal of the Moffitt Cancer Center
Prognostic Significance of Myopenia, Myosteatosis, and Frailty in Older Patients With Prostate Cancer Undergoing Definitive Radiotherapy.
Article in Cancer control : journal of the Moffitt Cancer Center. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
IntroductionThis study aimed to evaluate the independent associations of myopenia, myosteatosis, and frailty with survival outcomes in older patients with prostate cancer undergoing definitive radiotherapy.MethodsA total of 124 patients aged ≥65 years who received definitive radiotherapy for localized or locally advanced prostate cancer between 2014 and 2023 were retrospectively analyzed. Myopenia and myosteatosis were quantified using the psoas muscle index (PMI) and Hounsfield unit average calculation (HUAC), respectively. Comorbidity-based frailty was assessed using the modified frailty index-11 (mFI-11). The cut-off points for the PMI and HUAC were determined using receiver operating characteristic (ROC) curve analysis. Univariate and parsimonious multivariable Cox regression analyses were used to examine the prognostic value of these markers for progression-free survival (PFS) and overall survival (OS).ResultsThe median age of the patients was 72 years (range: 65-87). According to the mFI-11, 47.6% of the patients were classified as frail. The cut-off values for PMI and HUAC were 2.0 cm
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.