Evidence map›Paper›PMID 42012958›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

The intestinal microbiota impacts nutritional immunity and resistance to

Erin R Green, Nicholas M Negretti, Tess H Brunner, Nicolas G Shealy, Felipe A Moser, Sydney L Drury, Kacie A Traina, Valeria M Reyes Ruiz, Tzushan S Yang, Christopher J Lehmann and 6 more

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

Erin R GreenDepartment of Microbiology, University of Chicago, Chicago, IL 60637.
Nicholas M NegrettiDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37232.
Tess H BrunnerDepartment of Microbiology, University of Chicago, Chicago, IL 60637.
Nicolas G ShealyDepartment of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232.
Felipe A MoserDepartment of Biochemistry, Vanderbilt University, Nashville, TN 37232.
Sydney L DruryDepartment of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232.
Kacie A TrainaDepartment of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232.
Valeria M Reyes RuizDepartment of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232.
Tzushan S YangDepartment of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232.
Christopher J LehmannDuchossois Family Institute, University of Chicago, Chicago, IL 60637.
Mariana X ByndlossDepartment of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232.ORCID 0000-0002-2122-4156
Raf van de PlasDepartment of Biochemistry, Vanderbilt University, Nashville, TN 37232.
Joseph P ZackularDivision of Protective Immunity, Children's Hospital of Philadelphia, Philadelphia, PA 19104.
Samuel H LightDepartment of Microbiology, University of Chicago, Chicago, IL 60637.ORCID 0000-0002-8074-1348
Jennifer M S SucreDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37232.
Eric P SkaarDepartment of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232.ORCID 0000-0001-5094-8105

Funding

TRAINING PROGRAM IN ENVIRONMENTAL TOXICOLOGYT32ES007028 · NIEHS · VANDERBILT UNIVERSITY · PI F PETER Guengerich, Fiona Edith Harrison · 1985 to 2026
$15.7M
Host-mediated zinc sequestration during Acinetobacter baumannii infectionR01AI101171 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WALTER J. CHAZIN, DAVID P. GIEDROC · 2013 to 2026
$8.2M
TRAINING PROGRAM IN CELLULAR, BIOCHEMICAL, &MOLECULAR ST32GM008554 · NIGMS · VANDERBILT UNIVERSITY · PI PATTON, JAMES G. · 1995 to 2020
$7.4M
Vanderbilt University Biomolecular Multimodal Imaging Center for 3-Dimensional Mapping of the Human KidneyU54DK134302 · NIDDK · VANDERBILT UNIVERSITY · PI CAPRIOLI, RICHARD M, SPRAGGINS, JEFFREY M · 2022 to 2025
$7.1M
Interdisciplinary Training Program in Lung ResearchT32HL094296 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Ray Stokes Peebles · 2008 to 2026
$6.3M
Medical Scientist National Research Service AwardT32GM150375 · NIGMS · UNIVERSITY OF CHICAGO · PI Raghavendra G Mirmira · 2023 to 2026
$5.5M
Molecular mapping of microbial communities at the host-pathogen interface by multi-modal 3-dimensional imaging mass spectrometryR01AI138581 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Eric P Skaar, Jeffrey M Spraggins · 2018 to 2026
$5.2M
Elucidating Molecular Drivers of Aging and Alzheimer's Disease via Multimodal Imaging Mass SpectrometryR01AG078803 · NIA · VANDERBILT UNIVERSITY · PI Rena A. S. Robinson, Matthew Schrag · 2022 to 2026
$3.5M
Integrated Molecular and Cellular Drivers of AlveologenesisR01HL168556 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Jennifer MalcolmSrygley Sucre · 2023 to 2026
$2.8M
Molecular interactions in the gut microbiota during early life colonization and perturbationR35GM138369 · NIGMS · CHILDREN'S HOSP OF PHILADELPHIA · PI Joseph Paul Zackular · 2020 to 2026
$2.7M
Mechanisms of Salmonella-mediated disruption of colonization resistance in the inflamed gutR01AI168302 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Mariana Xavier Byndloss · 2022 to 2026
$2.4M
Obesogenic diet-induced intestinal epithelium repair responses link dysbiosis and cardiovascular diseaseR01DK131104 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Mariana Xavier Byndloss · 2022 to 2026
$2.4M
Burroughs Wellcome Fund (BWF) 022792HHMI (HHMI) GT15104HHS | NIH | Advanced Research Projects Agency for Health (ARPA-H) 1AY2AX000077NHLBI NIH HHS K08 HL143051NHLBI NIH HHS R01 HL168556NHLBI NIH HHS T32 HL094296NIAID NIH HHS K22 AI166265NIAID NIH HHS R01 AI101171NIAID NIH HHS R01 AI138581NIAID NIH HHS R01 AI168302NIA NIH HHS R01 AG078803NIDDK NIH HHS R01 DK131104NIDDK NIH HHS U54 DK134302NIEHS NIH HHS T32 ES007028NIGMS NIH HHS R35 GM138369NIGMS NIH HHS R35 GM146969NIGMS NIH HHS T32 GM008554NIGMS NIH HHS T32 GM150375Pew Charitable Trusts (Pew) 2022-A-19568
6 · The paper itself

Abstract

Broad-spectrum antibiotics are frequently administered to intensive care unit patients as part of empiric care. This treatment has been associated with subsequent infections by the emerging nosocomial pathogen

Indexed as

Acinetobacter baumanniiAcinetobacter InfectionsGastrointestinal MicrobiomePneumonia, BacterialAnimalsAnti-Bacterial AgentsDysbiosisFecal Microbiota TransplantationFemaleHumansLipocalin-2LungMiceMice, Inbred C57BLNeutrophilsAnti-Bacterial AgentsLipocalin-2Acinetobacter baumanniigut–lung axismicrobiotanosocomial infectionsnutritional immunity

Identifiers

PMID42012958
PMCPMC13123906

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.