ArticleJournal of veterinary internal medicine2026
Clinical outcomes and association with disease progression and survival of subclinical bacteriuria in cats with chronic kidney disease: a multicenter retrospective study.
Article in Journal of veterinary internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- 2026 iCatCare consensus guidelines on the diagnosis and management of chronic kidney disease in cats.Journal of feline medicine and surgery · 2026Guideline
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSubclinical bacteriuria (SBU) is frequently encountered in cats with chronic kidney disease (CKD), but it remains unclear if it is associated with survival and disease progression. HYPOTHESIS/
objectivesTo determine the association of SBU with survival time and disease progression in cats with CKD. ANIMALS: Two hundred eighty-seven client-owned CKD cats diagnosed according to the IRIS guidelines.
methodsRetrospective multicenter study from January 2015 to May 2024. Cats were included from 4 veterinary teaching hospitals if they were diagnosed with CKD, had a documented urine culture result from cystocentesis and no signs of lower urinary tract disease (LUTS). Cats were divided into SBU group and control group, based on culture results. Medical records and long-term outcomes were reviewed. Multivariate Cox proportional hazards regression was used for survival analysis, and frequency of CKD progression was compared.
resultsSBU was not significantly associated with survival (hazard ratio [HR] = 0.68; 95% CI, 0.39-1.16; P = .16) or CKD progression (P = .84). Higher plasma creatinine (HR = 1.02; 95% CI, 1.00-1.03; P = .01) and lower body condition score (HR = 0.80; 95% CI, 0.67-0.95; P = .01) were associated with reduced survival. In SBU cats, antimicrobial treatment was prescribed in 85 cats (78%) and did not prevent bacterial persistence or recolonization. Progression to bacterial cystitis or pyelonephritis was observed with or without antimicrobial treatment. CONCLUSIONS AND CLINICAL IMPORTANCE: SBU in cats with CKD do not seem to be significantly associated with death or affect disease progression. These findings do not support routine antimicrobial treatment of SBU in cats CKD.
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