Evidence map›Paper›PMID 42012733›Full record

ArticleEuropean radiology experimental2026

Diagnostic performance and reader confidence of MRI-derived CT-like images in patients with femoral head necrosis.

Felix L Herr, Natascha Hohmann, Christian Dascalescu, Veronika Gottfried, Markus Bormann, Boj F Hoppe, Lennart Schröder, Jens Ricke, Boris M Holzapfel, Alexandra Gersing and 3 more

Abstract read
In one paragraph

Article in European radiology experimental, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Felix L HerrDepartment of Radiology, University Hospital, LMU Munich, Munich, Germany. felix.herr@med.uni-muenchen.de.ORCID http://orcid.org/0009-0004-0835-0328
Natascha HohmannDepartment of Radiology, University Hospital, LMU Munich, Munich, Germany.
Christian DascalescuDepartment of Radiology, University Hospital, LMU Munich, Munich, Germany.
Veronika GottfriedDepartment of Radiology, University Hospital, LMU Munich, Munich, Germany.
Markus BormannDepartment of Orthopaedics and Trauma Surgery, Orthopaedic Oncology, Musculoskeletal University Center Munich (MUM), University Hospital, LMU Munich, Munich, Germany.
Boj F HoppeDepartment of Radiology, University Hospital, LMU Munich, Munich, Germany.
Lennart SchröderDepartment of Orthopaedics and Trauma Surgery, Orthopaedic Oncology, Musculoskeletal University Center Munich (MUM), University Hospital, LMU Munich, Munich, Germany.
Jens RickeDepartment of Radiology, University Hospital, LMU Munich, Munich, Germany.
Boris M HolzapfelDepartment of Orthopaedics and Trauma Surgery, Orthopaedic Oncology, Musculoskeletal University Center Munich (MUM), University Hospital, LMU Munich, Munich, Germany.
Alexandra GersingDepartment of Neuroradiology, University Hospital, LMU Munich, Munich, Germany.
Nina HesseDepartment of Radiology, University Hospital, LMU Munich, Munich, Germany.
Jörg Arnholdt *Department of Orthopaedics and Trauma Surgery, Orthopaedic Oncology, Musculoskeletal University Center Munich (MUM), University Hospital, LMU Munich, Munich, Germany.
Paul Reidler *Department of Radiology, University Hospital, LMU Munich, Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Femoral head necrosis (FHN) requires accurate imaging for staging and treatment planning. While MRI is sensitive, conventional sequences may miss subchondral fractures. A CT-like MRI sequence combines CT-like structural detail with soft-tissue contrast. We evaluated its performance for Association Research Circulation Osseous (ARCO) staging compared with MRI and radiography. In this retrospective study, 21 patients (33 hips) with confirmed FHN underwent radiography and MRI, including T1- and T2-weighted sequences and a T1-weighted gradient-echo CT-like sequence. Two musculoskeletal imaging specialists assessed ARCO stage, reader confidence, and image quality. Interrater reliability was evaluated using the intraclass correlation coefficient, intermodality agreement with weighted Cohen's κ, and modality comparisons with Wilcoxon signed-rank tests. CT-like MRI demonstrated higher ARCO staging than radiography (p = 0.004), T1-weighted (p = 0.031), and T2-weighted MRI (p = 0.046). Upstaging compared with conventional modalities occurred in 6 of 33 hips (18.2%). Reader confidence was highest for CT-like MRI (all p ≤ 0.003), and image quality was superior compared with T1- and T2-weighted MRI (both p < 0.001). Agreement in ARCO staging was excellent with T1-weighted and T2-weighted images and substantial with radiography. CT-like MRI improved image quality and diagnostic confidence, enabling more accurate FHN assessment and detection of subchondral collapse missed by conventional MRI. RELEVANCE STATEMENT : CT-like MRI improves detection of early femoral head collapse, enabling more accurate staging and treatment planning. KEY POINTS : Femoral head necrosis requires precise imaging to accurately stage the disease. Conventional MRI may miss early subchondral femoral head fractures. CT-like MRI enhances visualization of bone microstructure, diagnostic confidence and image quality. Improved staging with CT-like MRI may influence clinical management.

Indexed as

Femur Head NecrosisMagnetic Resonance ImagingTomography, X-Ray ComputedAdultAgedFemaleHumansMaleMiddle AgedObserver VariationReproducibility of ResultsRetrospective StudiesFemur head necrosisMagnetic resonance imagingRadiographyReproducibility of resultsTomography (X-ray computed)

Identifiers

PMID42012733
PMCPMC13100174

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.