ArticlePediatric surgery international2026
International disparities in biliary atresia outcomes.
Article in Pediatric surgery international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
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Abstract
The Japanese Biliary Atresia Registry, reported by Okubo et al., provides a comprehensive long-term perspective on biliary atresia (BA) across 3951 patients (1989–2023). With jaundice clearance rates exceeding 60% and 10-year native liver survival of 50.5%, outcomes in Japan remain consistently superior to those reported in Western cohorts. These disparities are likely multifactorial. BA represents a heterogeneous phenotype shaped by genetic, immunological, environmental, and developmental factors that may differ across populations. The lower prevalence of biliary atresia splenic malformation syndrome in Japan (2.2% vs. 8–15%) may partly contribute but does not fully explain the gap. Differences in management strategies, including earlier surgery, greater use of revision Kasai portoenterostomy, and adjuvant therapies, may also play a key role.
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