ArticleJournal of ethnicity in substance abuse2026
Evaluating risk factors and protective clinical interventions for opioid use disorder and overdose in American Indian/Alaska Native populations.
Article in Journal of ethnicity in substance abuse, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Emergency Department Peer Recovery Support Services for Individuals with Substance Use Disorders: A Systematic Review of Comparative Studies.Substance abuse and rehabilitation · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
American Indian/Alaska Native (AI/AN) populations often experience higher rates of opioid use disorder (OUD) and opioid overdose deaths compared to other racial/ethnic groups. This study evaluates modifiable risk factors and protective clinical interventions for OUD and overdose prevention interventions among AI/AN patients to understand potential points of intervention. This retrospective cohort study utilized electronic health record data from the Oracle Cerner Real-World Database. The sample included AI/AN individuals aged ≥12 years with an index encounter for opioid prescription or a new OUD diagnosis between January 2006 - January 2021. Modifiable risk factors and protective clinical interventions or overdose prevention interventions included opioid and benzodiazepine co-occurrence, polysubstance use, and interventions such as medications for opioid use disorder (MOUD), safe substance use education, naloxone prescription, and urine drug testing. Adjusted hazard ratios (aHRs) were obtained via Cox Proportional-Hazard regressions. Individuals with a co-occurrence of opioids and benzodiazepines had a higher risk of developing OUD (aHR 1.32, 95% CI 1.19-1.45). Polysubstance use was significantly associated with an increased risk of OUD (aHR 1.85, 95% CI 1.58-2.17) and opioid overdose (aHR 1.47, 95% CI 1.04-2.09). Receiving safe substance use education was associated with a 19% lower risk of OUD (aHR 0.81, 95% CI 0.68-0.98). Prescriptions for naloxone (aHR 0.39, 95% CI 0.17-0.89) or MOUD (aHR 0.25, 95% CI 0.13-0.49) were associated with a lower risk for opioid overdose. The findings highlight key clinical practices and patient behaviors that may significantly affect the risk of OUD and overdose for AI/AN populations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.