ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2026
Electronic Clinical Quality Measures of Antibiotic Use in Hospitalized Adults With Uncomplicated Community-Acquired Pneumonia.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
Abstract
backgroundCommunity-acquired pneumonia (CAP) is the top indication for inpatient antibiotic use and overuse. We describe the development of 2 electronic clinical quality measures (eCQMs) assessing the percentage of hospitalized patients with uncomplicated CAP who had unsupported antibiotic duration beyond 5 days and empiric antibiotics targeting methicillin-resistant Staphylococcus aureus and/or Pseudomonas aeruginosa.
methodsBoth eCQMs were developed based on clinical guidelines, literature, and expert feedback and then specified electronically. The eCQMs were applied to patient data from 2 academic medical centers and 109 Department of Veterans Affairs (VA) healthcare systems to evaluate importance, reliability, validity, and feasibility, as defined by the Centers for Medicare and Medicaid Services.
resultsAcross all hospitals, the mean percentage of eligible patients with unsupported excess duration and inappropriate empiric antibiotic use ranged from 40% to 55% and from 17% to 56%, respectively. Within the VA cohort, reliability (median [first-tenth decile, n]) for duration and empiric eCQMs was high: 93% (63%-97%, 28 238) and 91% (63%-96%, 47 034), respectively. When compared to chart review at 1 academic hospital, both eCQMs had high sensitivity (96%, both) and specificity (92% and 93% for duration and empiric eCQMs, respectively). Feasibility was maximized by using only data elements in structured electronic health record fields. Some technically complex elements (eg, clinical stability) were retained for face validity.
conclusionsTwo eCQMs identifying unsupported excess antibiotic duration and inappropriately broad empiric antibiotic use in patients with uncomplicated CAP had high importance, reliability, validity, and feasibility. These eCQMs could be benchmarked to assist antibiotic stewardship programs in understanding and improving their antibiotic use.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.