ReviewJournal of virology2026
Behind the membranous curtain-lipid dynamics and functions in coronaviral replication.
Review in Journal of virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
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Authors and funding
2 authors.
Funding
Abstract
Lipids are naturally occurring hydrophobic biomolecules characterized by remarkable structural diversity. This includes various types of head groups, varying fatty acid chain lengths, degrees of unsaturation, and stereochemical configurations. Such variability enables lipids to serve multiple biological functions, such as forming membranes, storing energy, and facilitating signaling. Given their diverse roles, it is not surprising that approximately 5% of genes in eukaryotic cells are involved in lipid biosynthesis pathways. The multifunctional nature of lipids also makes them attractive targets for pathogens, including viruses, as cellular lipids are involved in and manipulated throughout every stage of viral replication. In the initial phase of replication, viruses exploit existing cellular lipids for entry and trafficking. After the replication is established and viral proteins are processed, extensive reprogramming of lipid synthesis and redistribution supports viral replication, assembly, and other processes. This review focuses on how coronaviruses, especially severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), utilize different lipid species and related cellular enzymes to interfere with lipid dynamics and functions and how this affects the different stages of coronaviral replication
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