Evidence map›Paper›PMID 42012160›Full record

ArticleApplied and environmental microbiology2026

When neighbors control metabolite fate: consequences for plant pathogen virulence and biocontrol outcomes.

Carlos N Lozano-Andrade, Joana I Pires Queiroz, Lars Jelsbak

Abstract readComment
In one paragraph

Article in Applied and environmental microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Carlos N Lozano-AndradeMicrobiome Interactions and Engineering Group, Department of Biotechnology and Biomedicine, Technical University of Denmark, Kgs. Lyngby, Denmark.ORCID 0000-0003-2805-4505
Joana I Pires QueirozMicrobiome Interactions and Engineering Group, Department of Biotechnology and Biomedicine, Technical University of Denmark, Kgs. Lyngby, Denmark.ORCID 0009-0004-0151-8482
Lars JelsbakMicrobiome Interactions and Engineering Group, Department of Biotechnology and Biomedicine, Technical University of Denmark, Kgs. Lyngby, Denmark.ORCID 0000-0002-5759-9769

Funding

Danmarks Frie Forskningsfond 10.46540/4307-00192BDanmarks Grundforskningsfond DNRF137Novo Nordisk Fonden NNF24OC0093315
6 · The paper itself

Abstract

Microbial interactions can profoundly influence the activity of bioactive metabolites in plant-associated communities. De Rop et al. show that community members enzymatically degrade cyclic lipopeptides (CLiPs), metabolites that act both as virulence factors in plant pathogens and antimicrobial agents in biological control (J. De Rop, D. Prasad, N. Geudens, L. Zhou, et al., Appl Environ Microbiol 92:e01524-25, 2026, https://doi.org/10.1128/aem.01524-25). By neutralizing these molecules, microbes determine whether CLiP-mediated activities persist or collapse, revealing that metabolite function depends on community-mediated turnover and highlighting an underappreciated ecological layer that shapes plant disease and biocontrol outcomes.

Indexed as

LipopeptidesMicrobial InteractionsPlant DiseasesPlantsPeptides, CyclicVirulenceVirulence FactorsLipopeptidesPeptides, CyclicVirulence Factorsantivirulencebiocontrolbiotransformationcyclic lipopeptidemicrobial interactionplant pathogenssecondary metabolites

Identifiers

PMID42012160
PMCPMC13188892

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.